Research Paper Volume 14, Issue 21 pp 8661—8687

Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging

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Figure 7. Krill oil improves healthspan. (A) The learning index was calculated from a positive association with butanone in wild type and PD animals at adult day 6 (n = 150 individuals, two independent experiments, error bars, s.e.m; NS, *p < 0.05; one-way ANOVA followed by Bonferroni’s multiple comparison test). (B) Quantification of pharyngeal pumping frequency (Hz) monitored in wild type and PD animals using the NemaMetrix screenchip based assay. The column scatter plot represents pharyngeal pumping frequency of adult day 3 animals (n = 15–20 individuals, Error bars, s.e.m NS and **P ≤ 0.001, ****p < 0.0001; one-way ANOVA followed by Bonferroni’s multiple comparison test). (C) Predicted biological age of wild type and PD animals in response to krill oil using BiTAge calculator. (D) TEM image of day 9 old in PD animals, boxed area represents the cuticle (scale bar 2000 nm).