Research Paper Volume 14, Issue 21 pp 8856—8875
Polydatin administration attenuates the severe sublesional bone loss in mice with chronic spinal cord injury
Figure 9. PLD activated Wnt/β-catenin signaling pathway in the femurs of chronic SCI mice. (A) SOST, Wnt3a, Lrp5 and ctnnb1 mRNA levels were determined by qRT-PCR method. (B) Immunoblot showing active β-catenin and total β-catenin levels. The protein levels of β-catenin were adjusted as relative values to GAPDH. Data are expressed as mean ± S.D.; n=5 to 7 per group; *P < 0.05, vs. the Sham group; #P < 0.05, vs. the SCI group.