Research Paper Volume 14, Issue 23 pp 9466—9483
Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation
Figure 7. Testing the efficacy of two forms of vitamin B3 on CSC propagation. (A) Nicotinamide, also known as niacinamide, significantly increases CSC propagation by >1.5-fold, at concentrations of 10 and 20 μM. (B) However, Nicotinic acid (or niacin) does not have any effect on mammosphere formation. Bar graphs are shown as the mean ± SEM; t-test, two-tailed test. ****p < 0.0001. Chemical formulae are indicated.