Research Paper Volume 14, Issue 23 pp 9393—9422
Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence
Figure 3. Common and cell-type specific gene expression changes with age. Significant differentially expressed genes (DEG) in old versus young samples. A Wilcoxon test was performed for each gene in each cell type between samples, with a logFold-Change (logFC) threshold of .25, and False-Discovery Rate (FDR) <1%. Red is upregulated with age, blue is downregulated. (A) All DEGs are shown by cell type. (B) Top 20 DEGs are shown by cell type, ranked by absolute logFC.