Research Paper Volume 14, Issue 23 pp 9393—9422
Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence
Figure 5. Identification of a small population of senescent cells in the fast skeletal muscle. (A) Subtypes of fast-skeletal muscle cells (UMAP, all samples). (B) Cluster 5 is circled, with expression of LRRK2, CDKN1A, MYH8, COL19A1 and TNNT3. (C) Difference in proportions between young and old for all subtypes. Significance of the t-test between young and old is shown at the top of 5C.