Research Paper Volume 15, Issue 1 pp 70—91

Figure 5. Smyd2 heterozygous knockout mice ameliorates senescence-associated phenotypes upon Ang II infusion. Smyd2^+/− mice and their wild-type littermates (WT) were infused with Ang II for 4 weeks. (A) Immunoblots of the proinflammatory mediators (COX-2 and VCAM-1). (B, C) The immunofluorescence analysis of Smyd2 with p53 or VCAM-1 in the cross-sectional area of blood vessels. Scale bars, 100 μm. Data are presented as the mean ± SEMs, ^***p < 0.001, each acquired from three individual experiments (n = 3).