Research Paper Volume 15, Issue 1 pp 179—192
lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin
Figure 8. HCG11 inhibited the proliferation of HR-positive BC cells in vivo. (A) The transfection efficiency in MCF-7 cells were examined by qRT-PCR. (B) Representative images of xenograft tumors in nude mice. (C) Average tumor size of nude mice. (D) Average tumor weight of nude mice. (E) Extract protein from tumors and measuring the expression of PCNA, SRSF1 and β-catenin by Western blot. (F) Immunohistochemistry (IHC) staining of PCNA, SRSF1 and β-catenin in xenografts tumors. ***p<0.001, **** p<0.0001.