Research Paper Volume 15, Issue 1 pp 246—260
Mitoquinone shifts energy metabolism to reduce ROS-induced oxeiptosis in female granulosa cells and mouse oocytes
Figure 1. MitoQ attenuates ROS-induced mitochondrial dysfunction in human granulosa cells. We treated GC cells with MitoQ (10 nM) for 24 h and analyzed mitochondrial function. Measurements of (A) cellular, (B) mitochondrial ROS, (C) mitochondrial mass, and (D) mitochondrial membrane potential (Δψm) by flow cytometry. *p < 0.05, and ***p < 0.001 compared to the control. ##p < 0.01 and ###p < 0.001 compared to ROS only.