Research Paper Volume 15, Issue 3 pp 734—747

MiR-181a-5p promotes osteogenesis by targeting BMP3

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Figure 1. Differentially expressed microRNAs in GSE93883. (A) Heatmap of microRNA expression among six healthy (Con) and six osteoporotic (OP) samples. (B) A volcano plot of microRNAs by setting the cutoff as a log2 fold change of > 1 and a P value of < 0.5. Gray color indicates non-significant microRNAs, while yellow or purple color represents up- or down-regulated microRNAs. The black arrow indicates miR-181a-5p. (C) mRNA level of miR-181a-5p in healthy controls and osteoporotic patients in GSE93883.