Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 15, Issue 3

14 February, 2023
pp 597—881

About the Cover

The cover features Figure 4 "Platelet depletion impairs amyloid beta phagocytosis by microglia" from de Sousa et al.

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Editorials

Harnessing the vasculo-protective potential of microglia

Sebok K. Halder, Arjun Sapkota, Richard Milner,

https://doi.org/10.18632/aging.204509 pp 597—598

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Untangling IGF-I signaling in the aging brain

Jonathan Zegarra-Valdivia, Angel Nuñez, Ignacio Torres Aleman,

https://doi.org/10.18632/aging.204507 pp 599—600

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Research Papers

Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity

Pedro S. Marra, Takehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba, Zoe-Ella M. Anderson, Manisha Modukuri, Gloria Chang, Tammy Tran, Masaaki Iwata, Hyunkeun Ryan Cho, Gen Shinozaki,

https://doi.org/10.18632/aging.204498 pp 601—616

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Epigenetic age and lung cancer risk in the CLUE II prospective cohort study

Dominique S. Michaud, Mei Chung, Naisi Zhao, Devin C. Koestler, Jiayun Lu, Elizabeth A. Platz, Karl T. Kelsey,

https://doi.org/10.18632/aging.204501 pp 617—629

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Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice

Diana M. Bessa de Sousa, Ariane Benedetti, Barbara Altendorfer, Heike Mrowetz, Michael S. Unger, Katharina Schallmoser, Ludwig Aigner, Kathrin Maria Kniewallner,

https://doi.org/10.18632/aging.204502 pp 630—649

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The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Trisha A. Staab, Grace McIntyre, Lu Wang, Joycelyn Radeny, Lisa Bettcher, Melissa Guillen, Margaret P. Peck, Azia P. Kalil, Samantha P. Bromley, Daniel Raftery, Jason P. Chan,

https://doi.org/10.18632/aging.204515 pp 650—674

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Ros-mediated mitochondrial oxidative stress is involved in the ameliorating effect of ginsenoside GSLS on chlorpyrifos-induced hepatotoxicity in mice

Hongyan Pei, Silu Liu, Jianning Zeng, Jinze Liu, Hong Wu, Weijia Chen, Zhongmei He, Rui Du,

https://doi.org/10.18632/aging.204298 pp 675—688

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The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer

Xiaowei Chen, Luhong Xie, Kun Qiao, Xiaoyu Zhu, Ji Ren, Yujie Tan,

https://doi.org/10.18632/aging.204459 pp 689—704

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miRNA-874-3p inhibits the migration, invasion and proliferation of breast cancer cells by targeting VDAC1

Housheng Yang, Zhiwen Wang, Shuang Hu, Lu Chen, Wei Li, Zhongyi Yang,

https://doi.org/10.18632/aging.204474 pp 705—717

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Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts

Shi-Yu Wang, Jin-Hai Jiang, Si-Yuan Liu, Jie Zhang, Xiang Gao, Hang Liu, Kai-Xin Ke, Yue Jiang, Lu Liu, Bai-Cheng He,

https://doi.org/10.18632/aging.204504 pp 718—733

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MiR-181a-5p promotes osteogenesis by targeting BMP3

Ze Long, Pengcheng Dou, Weiliang Cai, Minzhi Mao, Ren Wu,

https://doi.org/10.18632/aging.204505 pp 734—747

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Intrinsic capacity differs from functional ability in predicting 10-year mortality and biological features in healthy aging: results from the I-Lan longitudinal aging study

Wei-Ju Lee, Li-Ning Peng, Ming-Hsien Lin, Ching-Hui Loh, Fei-Yuan Hsiao, Liang-Kung Chen,

https://doi.org/10.18632/aging.204508 pp 748—764

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Senolytic effect of high intensity interval exercise on human skeletal muscle

Wei-Horng Jean, Yu-Wen Hsieh, Li-Fan Lai, Luthfia Dewi, Yu-Chieh Liao, Mengxin Ye, Szu-Hsien Yu, Chung-Lan Kao, Chih-Yang Huang, Chia-Hua Kuo,

https://doi.org/10.18632/aging.204511 pp 765—776

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Comparison of the mutation patterns between tumor tissue and cell-free DNA in stage IV gastric cancer

Ching-Yun Kung, Wen-Liang Fang, Yi-Ping Hung, Kuo-Hung Huang, Ming-Huang Chen, Yee Chao, Shih-Chieh Lin, Anna Fen-Yau Li, Su-Shun Lo, Chew-Wun Wu,

https://doi.org/10.18632/aging.204512 pp 777—790

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Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing

Hongliang Yang, Yan Zhang, Zhenwu Du, Tengfei Wu, Chun Yang,

https://doi.org/10.18632/aging.204513 pp 791—809

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Comprehensive analysis of BUBs gene family in lung adenocarcinoma with immunological analysis

Xiaojuan Li, Tianqi Wang, Mi Li, Xing Bao, Tian Ma, Caihong Yang, Hua Wu, Hao Li,

https://doi.org/10.18632/aging.204517 pp 810—829

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The context-dependent role of transforming growth factor-β/miR-378a-3p/connective tissue growth factor in vascular calcification: a translational study

You-Tien Tsai, Hsiang-Yuan Yeh, Chia-Ter Chao, Jenq-Wen Huang, Chih-Kang Chiang,

https://doi.org/10.18632/aging.204518 pp 830—845

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Thyroid cancer risk prediction model using m6A RNA methylation regulators: integrated bioinformatics analysis and histological validation

Wei Zhou, Junchao Lin, Jinqiang Liu, Rui Zhang, Aqiang Fan, Qibin Xie, Liu Hong, Daiming Fan,

https://doi.org/10.18632/aging.204525 pp 846—865

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Differential expression profile of urinary exosomal microRNAs in patients with mesangial proliferative glomerulonephritis

Rong Dai, Lei Zhang, Hua Jin, Dong Wang, Meng Cheng, Yunhui Xu, Haiyin Zhang, Yiping Wang,

https://doi.org/10.18632/aging.204527 pp 866—880

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Retraction

Retraction: LncRNA AK045171 protects the heart from cardiac hypertrophy by regulating the SP1/MG53 signalling pathway

Li Xu, Hongjiang Wang, Feng Jiang, Hao Sun, Dapeng Zhang,

https://doi.org/10.18632/aging.204530 pp 881

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