Research Paper Volume 15, Issue 3 pp 791—809

Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing

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Figure 6. Production HF-MSCs and HF-MSC-Exo with lncRNA H19. (A) qRT-PCR was utilized to identify the lncRNA H19 expression in mouse diabetic skin. *P<0.05 WT vs Diabetes. (B) qRT-PCR was utilized to identify the lncRNA H19 expression in HF-MSCs and HF-MSC-Exo. *P<0.05 MSC vs MSC-Exo. (C, D) qRT-PCR was employed to ascertain the efficiency of overexpressing or silencing lncRNA H19 in HF-MSCs and HF-MSC-Exo.**P<0.01, OE-H19 vs OE-NC ##P<0.01, sh-H19 vs sh-NC. (E) Subcellular localization of lncRNA H19 in HFMSCs detected by FISH (400×). Data measured are articulated as mean ± SD.