Research Paper Volume 15, Issue 3 pp 791—809

Figure 8. HF-MSC-Exo carrying lncRNA H19 promote mouse skin wound healing. (A) Representative images displaying mouse skin wound healing. (B) Wound histology after H&E staining. Tissue sections acquired from the wound site on day 14 after different injections were stained with antibodies against cytokeratin 14 and CD31. Scale bar = 200 μm. (C) Statistic the wound healing percent. (D) Quantitative analysis of the thickness of the new epidermis. (E) Quantitative analysis of the number of blood vessels. n = 3 per cohort. **P<0.01 OE-H19 contrasted with Control, ##P<0.01 OE-H19 compared with sh-H19. (F) Protein bond diagram of caspase-1 (I), IL-1β (J), IL-18 (K), and NLRP3 ascertained by western blot analysis. (G–J) Relative protein expression of caspase-1, IL-1β, IL-18, and NLRP3 normalized to GAPDH was evaluated by western blot analysis.