Figure 3. Differential expression of BUB1/3 at the transcriptional level in LUAD. (A, B) LUAD mRNA expression obtained by analyzing the GEPIA database and BUB1 mRNA expression in paired normal tissues. p <0.05, | Log2FC | > = 2. (C, D) LUAD mRNA expression in GEPIA and BUB3 mRNA expression in paired normal tissues. p values <0.05, | Log2FC | > = 2. (E) Expression of LUAD and BUB3 mRNA in paired normal tissues (data obtained from the TIMER database). p value <0.0001.