Research Paper Volume 15, Issue 7 pp 2450—2459

Figure 2. The clinical value of a prognostic gene-based risk model for osteosarcoma. (A) Patients’ risk scores were ranked from low to high, and scatter plots of risk scores and survival times were drawn. (B) Heatmap analysis of FKBP11 and BINP3 expression. (C) Univariate and multivariate regression analyses of factors correlated with osteosarcoma prognosis. (D) RNA was extracted from hFOB1.19 osteoblasts and osteosarcoma cells, and the expression of FKBP11 was measured by qRT-PCR. The protein expression of FKBP11 in hFOB1.19 and osteosarcoma cells was measured through western blotting. (E) Comparison of the expression of FKBP11 in osteosarcoma and paraneoplastic tissues. Scale bars represent 50 μm. ^*P < 0.05, ^**P < 0.01, and ^***p < 0.001.