Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 15, Issue 7

15 April, 2023
pp 2362—2812

About the Cover

The cover features Figure 5 "Epithelial and endothelial cell populations mediate p21-dependent inflammatory responses following chronic LPS inhalation" from Levi et al.

Explore This Issue

Editorials

A novel system to analyze oral frailty of mice

Tetsuya Goto, Eriko Kuramoto, Ayano Kitawaki,

https://doi.org/10.18632/aging.204568 pp 2362—2363

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Senescent cells enhance ischemic aging in the female heart

Daniele Torella, Nadia Salerno, Eleonora Cianflone,

https://doi.org/10.18632/aging.204585 pp 2364—2366

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Repurposing Canagliflozin to target brain aging

Hashan Jayarathne, Wanqing Liu, Marianna Sadagurski,

https://doi.org/10.18632/aging.204624 pp 2367—2368

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3-Deazaadenosine keeps senescence at bay

Ana Guerrero, Jesús Gil,

https://doi.org/10.18632/aging.204625 pp 2369—2370

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Commentary

Sex-specific hippocampal connectivity markers in mild cognitive impairment

Yuan Yang, Andriy Yabluchanskiy,

https://doi.org/10.18632/aging.204660 pp 2371—2372

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Research Papers

Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

Fares Al-Mansour, Abdullah Alraddadi, Buwei He, Anes Saleh, Marta Poblocka, Wael Alzahrani, Shaun Cowley, Salvador Macip,

https://doi.org/10.18632/aging.204616 pp 2373—2394

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p21 facilitates chronic lung inflammation via epithelial and endothelial cells

Naama Levi, Nurit Papismadov, Julia Majewska, Lior Roitman, Noa Wigoda, Raya Eilam, Michael Tsoory, Ron Rotkopf, Yossi Ovadya, Hagay Akiva, Ofer Regev, Valery Krizhanovsky,

https://doi.org/10.18632/aging.204622 pp 2395—2417

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Effect of deferoxamine and ferrostatin-1 on salivary gland dysfunction in ovariectomized rats

Yong-Il Cheon, Ji Min Kim, Sung-Chan Shin, Hyung-Sik Kim, Jin-Choon Lee, Gi Cheol Park, Eui-Suk Sung, Minhyung Lee, Byung-Joo Lee,

https://doi.org/10.18632/aging.204641 pp 2418—2432

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Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats

Brittney Yegla, Asha Rani, Ashok Kumar,

https://doi.org/10.18632/aging.204652 pp 2433—2449

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FKBP11 improves the malignant property of osteosarcoma cells and acts as a prognostic factor of osteosarcoma

Duo Zeng, Jiayu Li, Xuhui Yuan, Feng Cai, Bo Yu, Lang Liu, Qinchan Chen, FeiFei Zhang, Yiping Liang, Xiaofeng Tang, Yuanxiang Peng, Gaoyang Qu, Pengyun Wu, QuanHui Jiao, Longhua Sun, Xiao-Bin Lv, Qi Liao,

https://doi.org/10.18632/aging.204523 pp 2450—2459

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Relationship between advanced maternal age and decline of endometrial receptivity: a systematic review and meta-analysis

Jing Zhao, Bixia Huang, Ning Li, Xiaofei Wang, Bin Xu, Yanping Li,

https://doi.org/10.18632/aging.204555 pp 2460—2472

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High expression of serine protease 2 (PRSS2) associated with invasion, metastasis, and proliferation in gastric cancer

Haifeng Qin, Shushu Zhang, Linling Shen, Chenjian Mao, Guangyu Gao, Hui Wang,

https://doi.org/10.18632/aging.204604 pp 2473—2484

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NR5A2 as a potential target for exercise to improve metabolic syndrome

Lingxiu Meng, Fusheng Dong, Junguo Deng,

https://doi.org/10.18632/aging.204606 pp 2485—2502

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NCAPG as a novel prognostic biomarker in numerous cancers: a meta-analysis and bioinformatics analysis

Jie Lin, Gangyi Li, Yanping Bai, Yingjun Xie,

https://doi.org/10.18632/aging.204621 pp 2503—2524

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RNA helicase DDX5-induced circPHF14 promotes gastric cancer cell progression

Jia Wang, Chunjie Han, Jinsheng Wang, Qiu Peng,

https://doi.org/10.18632/aging.204623 pp 2525—2540

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Identification and validation of anoikis-associated gene SNCG as a prognostic biomarker in gastric cancer

Yi Li, Qin Pan, Mingxia Cheng, Zhengyuan Wu,

https://doi.org/10.18632/aging.204626 pp 2541—2553

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A novel inflammation-related signature for predicting prognosis and characterizing the tumor microenvironment in colorectal cancer

Jinna Li, Jiapeng Yang, Rui Xing, Ying Wang,

https://doi.org/10.18632/aging.204630 pp 2554—2581

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Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer

Xin Liu, Dandan Zhang, Jianping Hu, Sikai Xu, Chengyun Xu, Yang Shen,

https://doi.org/10.18632/aging.204631 pp 2582—2609

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Bioinformatics analysis and experimental validation of a novel autophagy-related signature relevant to immune infiltration for recurrence prediction after curative hepatectomy

Huaxiang Wang, Chengkai Yang, Dong Li, Ruling Wang, Yanbing Li, Lizhi Lv,

https://doi.org/10.18632/aging.204632 pp 2610—2630

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Biological function analysis of ARHGAP39 as an independent prognostic biomarker in hepatocellular carcinoma

Yongqi Ding, Yiyang Gong, Hong Zeng, Xuanrui Zhou, Zichuan Yu, Jingying Pan, Minqin Zhou, Shiwen Liu, Wei Lai,

https://doi.org/10.18632/aging.204635 pp 2631—2666

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Machine learning-based construction of immunogenic cell death-related score for improving prognosis and response to immunotherapy in melanoma

Guoyin Li, Huina Zhang, Jin Zhao, Qiongwen Liu, Jinke Jiao, Mingsheng Yang, Changjing Wu,

https://doi.org/10.18632/aging.204636 pp 2667—2688

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Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation

Haitao Yang, Xiao Feng, Xiangdong Tong,

https://doi.org/10.18632/aging.204639 pp 2689—2704

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Berberine mitigates intracerebral hemorrhage-induced neuroinflammation in a gut microbiota-dependent manner in mice

Jing Liu, Haotian Chen, Ting Yu, Xiongjie Fu, Cong Qian, Xiuqin Feng,

https://doi.org/10.18632/aging.204642 pp 2705—2720

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Pioglitazone reduces cardiovascular events and dementia but increases bone fracture in elderly patients with type 2 diabetes mellitus: a national cohort study

Chieh-Li Yen, Chao-Yi Wu, Chung-Ying Tsai, Cheng-Chia Lee, Yi-Jung Li, Wei-Sheng Peng, Jia-Rou Liu, Yuan-Chang Liu, Chang-Chyi Jenq, Huang-Yu Yang, Lai-Chu See,

https://doi.org/10.18632/aging.204643 pp 2721—2733

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Comprehensive analysis reveals TSEN54 as a robust prognosis biomarker and promising immune-related therapeutic target for hepatocellular carcinoma

Bidong Fu, Minqin Zhou, Gelin Song, Hong Zeng, Yiyang Gong, Yike Jiang, Yun Ke, Da Huang, Hong Peng, Qing Li,

https://doi.org/10.18632/aging.204645 pp 2734—2771

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Comprehensive analysis of cuproptosis-related immune biomarker signature to enhance prognostic accuracy in gastric cancer

Jie Li, Tian Yu, Juan Sun, Ziyang Zeng, Zhen Liu, Mingwei Ma, Zicheng Zheng, Yixuan He, Weiming Kang,

https://doi.org/10.18632/aging.204646 pp 2772—2796

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Long non-coding RNA HOXA11-AS regulates ischemic neuronal death by targeting miR-337-3p/YBX1 signaling pathway: protective effect of dexmedetomidine

Fei Yan, Pinxiao Wang, Xiaojian Yang, Fuli Wang,

https://doi.org/10.18632/aging.204648 pp 2797—2811

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Retraction

Retraction: FoxD2‐AS1 promotes glioma progression by regulating miR‐185‐ 5P/HMGA2 axis and PI3K/AKT signaling pathway

Wei Ni, Yaoxiong Xia, Yuxu Bi, Fan Wen, Dong Hu, Lin Luo,

https://doi.org/10.18632/aging.204664 pp 2812

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