Research Paper Volume 15, Issue 4 pp 1107—1129

Figure 10. Correlation analysis of EGFR, PD-L1 expression and immune cell infiltration in ESCC. (A–C) Boxplot showing the correlation between enrichment score and the level of infiltration of T cells, CD8 T cells and B cells in high and low EGFR expression subgroups. (D–F) The immune cell infiltration levels of T cells, CD8 T cells and B cells have correlation with EGFR expression. (G–I) Boxplot indicate the correlation between enrichment score and the level of infiltration of T cells, CD8 T cells and B cells in high and low PD-L1 expression subgroups. (J–L) The immune cell infiltration levels of T cells, CD8 T cells and B cells have correlation with PD-L1 expression. A positive value of the correlation coefficient (r) indicates a positive relationship between the two variables, and a negative value indicates a negative relationship. ^*, ^**, ^*** represents P < 0.05, P < 0.01, P < 0.001, respectively. ns represents “No significant”, Abbreviations: EGFR: Epidermal Growth Factor Receptor; PD-L1: programmed death-ligand 1; ESCC: Esophageal Squamous Cell Carcinoma.