Research Paper Volume 15, Issue 6 pp 1931—1943
Exosomal miR-370-3p increases the permeability of blood-brain barrier in ischemia/reperfusion stroke of brain by targeting MPK1
Figure 4. miR-370-3p aggravates I/R-induced BBB disruption. (A, B) The transendothelial electrical resistance of bEND.3 cells was measured using Millicell-ERS electrical resistance system. (C, D) The relative expressions of miR-370-3p in cerebral I/R rats with miR-370-3p mimics or inhibitors treatment. (E, F) Infraction volume and Evan blue leakage were used to evaluate BBB permeability with miR-370-3p mimics or inhibitor treatment. ns, not significant, ** p<0.01, *** p<0.005, **** p<0.001.