Research Paper Volume 15, Issue 6 pp 1977—2004
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice
Figure 6. Hsp22 overexpression pretreatment alleviates BV2 microglial cells inflammation and apoptosis induced by LPS. The protein band of IL-6 (A), TNF-α (B) and its expression (**p < 0.01, **p < 0.01 vs. Control; ns: p > 0.05, LPS vs. LPS+OE-Control; #p < 0.05, #p < 0.05 vs. LPS+OE-Control). (C) The protein band of Bax and its expression (D); The protein band of Bcl2 and its expression (***p < 0.005, *p < 0.01 vs. Control; ns: p > 0.05, LPS vs. LPS+OE-Control; #p < 0.05, #p < 0.05 vs. LPS+OE-Control).