Research Paper Volume 15, Issue 6 pp 1977—2004
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice
Figure 7. Hsp22 overexpression pretreatment alleviates hippocampus tissue apoptosis induced by LPS. (A, B) Representative images of Tunel-stained brain sections (×200) (***p < 0.005 vs. Control; ns: p > 0.05, LPS vs. LPS+Lv-Hsp22-NC; ###p < 0.005 vs. LPS+Lv-Hsp22-NC). (C) The protein band of Bax and its expression. (D) The protein band of Bcl2 and its expression. (*p < 0.05, ***p < 0.005 vs. Control; ns: p > 0.05, LPS vs. LPS+Lv-Hsp22-NC; #p < 0.05, #p < 0.05 vs. LPS+Lv-Hsp22-NC).