Research Paper Volume 15, Issue 6 pp 2158—2169
Reduction of NgR in perforant path protects neuronal morphology and function in APP/PS1 transgenic mice
Figure 5. Knockdown of NgR in the perforant path prevents inflammatory reaction in APP/PS1 transgenic mice. (A–F) The mRNA levels of M1 (TNF-α, IL1β and IL-6) and M2 (Arg1, Ym-1 and CD206) markers in the hippocampus determined by RT-PCR. Data are presented as mean ± SEM. n = 3-4 male mice/group. The statistical analysis was performed by Student’s t test. *P < 0.05; **P < 0.01.