Research Paper Volume 15, Issue 6 pp 2321—2346
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing’s sarcoma
Figure 9. Correlation of ANXA1 expression with immune cells and immunoinhibitors in sarcoma. (A) Heatmap of the correlation between ANXA1 expression and TILs in sarcoma: red represents a positive correlation, blue represents a negative correlation. (B) ANXA1 expression was positively correlated with infiltrating abundance of tcm_CD8, tcm_CD4, macrophage, treg, tfh, MDSC, tgd, NKT, act_DC and monocyte. (C) Heatmap of the correlation between ANXA1 expression and immunoinhibitors in sarcoma: red represents positive correlation, blue represents negative correlation. (D) ANXA1 expression was positively correlated with infiltrating abundance of HAVCR2, CSF1R, IL-10, LGALS9, IL10RB, PDCD1LG2, TGFB1, TGFBR1, TIGIT and CD96.