Research Paper Volume 15, Issue 7 pp 2525—2540

RNA helicase DDX5-induced circPHF14 promotes gastric cancer cell progression

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Figure 2. DDX5 promotes cancer cell growth and migration. (A) Colony formation of AGS and 7901 cells two weeks after transfection with the indicated vector. (B) CCK-8 assay of proliferation in AGS and 7901 cells following a time course of transfection with NC or DDX5. (C) EdU assay was conducted to test the effect of DDX5 expression on the proliferation of AGS and 7901 cells. Scale bar 100μm. (D) Transwell assay was conducted to test the effect of DDX5 expression on the migration of AGS and 7901 cells. Number of cells were counted and shown in the column graph on the right of the corresponding pictures. Data are mean ± SD of three independent experiments. * P < 0.05, ** P < 0.01. Scale bar 500μm.