Research Paper Volume 15, Issue 7 pp 2582—2609

Figure 4. Enrichment analysis of AIF-1-related partners. (A) The GeneMANIA database showed the AIF-1-interacting gene network. The size of the node indicates the intensity of the connections. The internode connection lines represent gene-gene interactions, and the line color represents the types of interactions. The node color represents the possible functions of the respective genes. (B) The AIF-1-correlated genes in TCGA projects and the expression correlation between AIF-1 and the top 10 selected genes, including TYROBP, GMGF, LAPTM5, SELPLG, C1orf162, LST1, SPI1, TNFAIP8L2, and MS4A6A, were analyzed. (C) The corresponding heatmap data in the exact cancer types are displayed.