Figure 7. Relationships between AIF-1 and immune regulators, TMB, and MSI. (A) The Spearman correlation heatmap depicts the relationships between AIF-1 expression and the 47 different types of immune regulators in pan-cancer. Red color denotes a positive correlation, whereas blue color signifies a negative correlation. (B) Correlations between AIF-1 expression and tumor mutation burden (TMB) across cancers. (C) Correlations between AIF-1 expression and microsatellite instability (MSI) across cancers. (*P < 0.05, **P < 0.01, and ***P < 0.001).