Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation

Haitao Yang; Xiao Feng; Xiangdong Tong

doi:doi:10.18632/aging.204639

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Research Paper Volume 15, Issue 7 pp 2689—2704

Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation

Figure 9. POU6F2-AS2 downregulation represses tumor growth in vivo. (A) The representative image of xenografted tumor tissues. (B and C) The growth curves and weight of xenografted tumor tissues. ^**P < 0.001 vs. sh-NC group. (D) miR-125b-5p and POU6F2-AS2 levels in xenografted tumor tissues. ^**P < 0.001 vs. sh-NC group. (E) E2F3 protein level in xenografted tumor tissues. ^**P < 0.001 vs. sh-NC group.