Heart rate variability as predictive factor for sudden cardiac death

Francesco Sessa; Valenzano Anna; Giovanni Messina; Giuseppe Cibelli; Vincenzo Monda; Gabriella Marsala; Maria Ruberto; Antonio Biondi; Orazio Cascio; Giuseppe Bertozzi; Daniela Pisanelli; Francesca Maglietta; Antonietta Messina; Maria P. Mollica; Monica Salerno

doi:doi:10.18632/aging.101386

Review Volume 10, Issue 2 pp 166—177

Heart rate variability as predictive factor for sudden cardiac death

Francesco Sessa^{1,

,}, Valenzano Anna^{1,

,}, Giovanni Messina^1,, Giuseppe Cibelli^1,, Vincenzo Monda^2,, Gabriella Marsala^3,, Maria Ruberto^4,, Antonio Biondi^5,, Orazio Cascio^6,, Giuseppe Bertozzi^1,, Daniela Pisanelli^1,, Francesca Maglietta^1,, Antonietta Messina^2,, Maria P. Mollica^2,, Monica Salerno^1,,

¹ University of Foggia, Department of Clinical and Experimental Medicine, Foggia, Italy
² Università degli Studi di Napoli Federico II, Department of Experimental Medicine, Naples, Italy
³ Struttura Complessa di Farmacia, Azienda Ospedaliero-Universitaria, Foggia, Italy
⁴ CRD Center, Santa Maria del Pozzo, Somma Vesuviana (NA), Italy
⁵ University of Catania, Department of Surgery, Catania, Italy
⁶ University of Catania, Department of Anatomy, Catania, Italy

* Equal contribution

Received: December 27, 2017 Accepted: February 9, 2018 Published: February 23, 2018

https://doi.org/10.18632/aging.101386
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Sessa F, Anna V, Messina G, Cibelli G, Monda V, Marsala G, Ruberto M, Biondi A, Cascio O, Bertozzi G, Pisanelli D, Maglietta F, Messina A, et al, . Heart rate variability as predictive factor for sudden cardiac death. Aging (Albany NY). 2018; 10:166-177. https://doi.org/10.18632/aging.101386

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Provider: 
        TY  - JOUR
        AU  - Sessa, Francesco 
        AU  - Anna, Valenzano 
        AU  - Messina, Giovanni 
        AU  - Cibelli, Giuseppe 
        AU  - Monda, Vincenzo 
        AU  - Marsala, Gabriella 
        AU  - Ruberto, Maria 
        AU  - Biondi, Antonio 
        AU  - Cascio, Orazio 
        AU  - Bertozzi, Giuseppe 
        AU  - Pisanelli, Daniela 
        AU  - Maglietta, Francesca 
        AU  - Messina, Antonietta 
        AU  - Mollica, Maria P. 
        AU  - Salerno, Monica 
        TI  - Heart rate variability as predictive factor for sudden cardiac death
        JO  - 
        JA  - Aging (Albany NY)
        VL  - 10
        IS  - 2
        PB  - 
        SN  - 
        UR  - https://doi.org/10.18632/aging.101386
        DO  - 10.18632/aging.101386
        SP  - 166
        EP  - 177
        PY  - 
        AB  - Sudden cardiac death (SCD) represents about 25% of deaths in clinical cardiology. The identification of risk factors for SCD is the philosopher's stone of cardiology and the identification of non-invasive markers of risk of SCD remains one of the most important goals for the scientific community.The aim of this review is to analyze the state of the art around the heart rate variability (HRV) as a predictor factor for SCD.HRV is probably the most analyzed index in cardiovascular risk stratification technical literature, therefore an important number of models and methods have been developed.Nowadays, low HRV has been shown to be independently predictive of increased mortality in post- myocardial infarction patients, heart failure patients, in contrast with the data of the general population.Contrariwise, the relationship between HRV and SCD has received scarce attention in low-risk cohorts. Furthermore, in general population the attributable risk is modest and the cost/benefit ratio is not always convenient.The HRV evaluation could become an important tool for health status in risks population, even though the use of HRV alone for risk stratification of SCD is limited and further studies are needed.
        ER  -

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Copyright: Sessa et al. This is an open‐access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Sudden cardiac death (SCD) represents about 25% of deaths in clinical cardiology. The identification of risk factors for SCD is the philosopher's stone of cardiology and the identification of non-invasive markers of risk of SCD remains one of the most important goals for the scientific community.

The aim of this review is to analyze the state of the art around the heart rate variability (HRV) as a predictor factor for SCD.

HRV is probably the most analyzed index in cardiovascular risk stratification technical literature, therefore an important number of models and methods have been developed.

Nowadays, low HRV has been shown to be independently predictive of increased mortality in post- myocardial infarction patients, heart failure patients, in contrast with the data of the general population.

Contrariwise, the relationship between HRV and SCD has received scarce attention in low-risk cohorts. Furthermore, in general population the attributable risk is modest and the cost/benefit ratio is not always convenient.

The HRV evaluation could become an important tool for health status in risks population, even though the use of HRV alone for risk stratification of SCD is limited and further studies are needed.

Review Volume 10, Issue 2 pp 166—177

Heart rate variability as predictive factor for sudden cardiac death

Received: December 27, 2017 Accepted: February 9, 2018 Published: February 23, 2018

Abstract

Corresponding Author

Keywords