Research Paper Volume 8, Issue 12 pp 3419—3429

Figure 3. Effect of QSOX on PrP^Sc amplification by PMCA. (A) Western blotting of PrP in the PMCA products after PrP^Sc amplification by PMCA in the presence of different amounts (0, 70 nM, and 140 nM) of QSOX for a round of PMCA. PrP^Sc was detected by Western blotting with the 3F4 antibody after a round of PMCA. The blot is a representative of three experiments. (B) Quantitative analysis of the amounts of PrP^Sc amplified by PMCA.