Figure 4. Knockdown of circRGNEF decreased the invasion ability of BC in vitro and in vivo. (A–C) Cell migration and invasion were assessed in T24 and UM-UC-3 cells using Transwell assays. Data are presented as the mean ± SD. ***P < 0.001 vs. NC. (D) Live imaging shows the effects of circRGNEF on metastasis of T24 cells 30 days after intravenous tail injection.