Zhavoronkov A, . Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections. . 12:6492-6510. https://doi.org/10.18632/aging.102988
Sargiacomo C, Sotgia F, Lisanti MP, . COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?. . 12:6511-6517. https://doi.org/10.18632/aging.103001
Yang J, Li H, Hu S, Zhou Y, . ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19. . 12:6518-6535. https://doi.org/10.18632/aging.103100
Zhang L, Pang R, Xue X, Bao J, Ye S, Dai Y, Zheng Y, Fu Q, Hu Z, Yi Y, . Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19. . 12:6536-6542. https://doi.org/10.18632/aging.103102
Du S, Shao J, Qi Y, Liu X, Liu J, Zhang F, . Long non-coding RNA ANRIL alleviates H2O2-induced injury by up-regulating microRNA-21 in human lens epithelial cells. . 12:6543-6557. https://doi.org/10.18632/aging.102800
Hou Y, Shi G, Guo Y, Shi J, . Epigenetic modulation of macrophage polarization prevents lumbar disc degeneration. . 12:6558-6569. https://doi.org/10.18632/aging.102909
Yao M, Zhang W, Ma W, Liu Q, Xing L, Zhao G, . Long non-coding RNA MALAT1 exacerbates acute respiratory distress syndrome by upregulating ICAM-1 expression via microRNA-150-5p downregulation. . 12:6570-6585. https://doi.org/10.18632/aging.102953
Er P, Qian D, Zhang W, Zhang B, Wei H, Zhang T, Chen X, Wang Y, Zhao J, Wang Q, Pang Q, Wang P, . The expression of PDGF-BB predicts curative effect in locally advanced esophageal squamous cell carcinoma treated by radiotherapy. . 12:6586-6599. https://doi.org/10.18632/aging.102993
Zhang Z, Wang W, Ma D, Xiong J, Kuang X, Zhang S, Fang Q, Wang J, . Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis. . 12:6611-6629. https://doi.org/10.18632/aging.102996
Chiu Y, Wu J, Yeh C, Yadav VK, Huang H, Wang L, . γ-Mangostin isolated from Garcinia mangostana L. suppresses inflammation and alleviates symptoms of osteoarthritis via modulating miR-124-3p/IL-6/NF-κB signaling. . 12:6630-6643. https://doi.org/10.18632/aging.103003
Zhang Y, Sun J, Yao H, Lin Y, Wei J, Hu G, Guo J, Li J, . Ultraconserved element uc.333 increases insulin sensitivity by binding to miR-223. . 12:6667-6679. https://doi.org/10.18632/aging.103020
Wang B, Zhang Y, Zhang H, Lin F, Tan Q, Qin Q, Bao W, Liu Y, Xie J, Zeng Q, . Long intergenic non-protein coding RNA 324 prevents breast cancer progression by modulating miR-10b-5p. . 12:6680-6699. https://doi.org/10.18632/aging.103021
Lee YY, Choi YS, Kim DW, Cheong JY, Song KY, Ryu MS, Lim IK, . Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21WAF1-PKCζ pathway in p16INK4a-silenced cells. . 12:6700-6732. https://doi.org/10.18632/aging.103029
Wang Y, Yu T, Zhou Y, Wang S, Zhou X, Wang L, Ou T, Chen Y, Zhou Y, Zhang H, Wang Y, Fan X, Chen P, et al, . Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. . 12:6733-6755. https://doi.org/10.18632/aging.103033
Cui J, Wang H, Zhang X, Sun X, Zhang J, Ma J, . Exosomal miR-200c suppresses chemoresistance of docetaxel in tongue squamous cell carcinoma by suppressing TUBB3 and PPP2R1B. . 12:6756-6773. https://doi.org/10.18632/aging.103036
Liu Y, Chang Y, Cai Y, . circTNFRSF21, a newly identified circular RNA promotes endometrial carcinoma pathogenesis through regulating miR-1227-MAPK13/ATF2 axis. . 12:6774-6792. https://doi.org/10.18632/aging.103037
Zhang X, Xu J, Yan R, Zhang Y, Hu Z, Fu H, You Q, Cai Q, Yang D, . FAM84B, amplified in pancreatic ductal adenocarcinoma, promotes tumorigenesis through the Wnt/β-catenin pathway. . 12:6808-6822. https://doi.org/10.18632/aging.103044
Lin J, Kuo W, Baskaran R, Kuo C, Chen Y, Chen WS, Ho T, Day CH, Mahalakshmi B, Huang C, . Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus. . 12:6852-6864. https://doi.org/10.18632/aging.103046
Yang C, Li Q, Chen X, Zhang Z, Mou Z, Ye F, Jin S, Jun X, Tang F, Jiang H, . Circular RNA circRGNEF promotes bladder cancer progression via miR-548/KIF2C axis regulation. . 12:6865-6879. https://doi.org/10.18632/aging.103047
Leong W, Xu W, Wang B, Gao S, Zhai X, Wang C, Gilson E, Ye J, Lu Y, . PP2A subunit PPP2R2C is downregulated in the brains of Alzheimer’s transgenic mice. . 12:6880-6890. https://doi.org/10.18632/aging.103048
Qi J, Liu S, Liu W, Cai G, Liao G, . Identification of UAP1L1 as tumor promotor in gastric cancer through regulation of CDK6. . 12:6904-6927. https://doi.org/10.18632/aging.103050
Huang R, Mao M, Lu Y, Yu Q, Liao L, . A novel immune-related genes prognosis biomarker for melanoma: associated with tumor microenvironment. . 12:6966-6980. https://doi.org/10.18632/aging.103054
Fang L, He J, Yan Y, Jia Q, Yu Y, Zhang R, Cheng J, Sun Y, . Blastocyst-stage embryos provide better frozen-thawed embryo transfer outcomes for young patients with previous fresh embryo transfer failure. . 12:6981-6989. https://doi.org/10.18632/aging.103055
Han B, Sun Y, Yang D, Zhang H, Mo S, Chen X, Lu H, Mao X, Hu J, . USP22 promotes development of lung adenocarcinoma through ubiquitination and immunosuppression. . 12:6990-7005. https://doi.org/10.18632/aging.103056
Kupiec A, Adamik B, Forkasiewicz-Gardynik K, Goździk W, . Intra-operative hyperoxia and the risk of delirium in elderly patients after cardiac surgery. . 12:7006-7014. https://doi.org/10.18632/aging.103058
Hu T, Shi J, Fang J, Wang Q, Chen Y, Zhang S, . Quercetin ameliorates diabetic encephalopathy through SIRT1/ER stress pathway in db/db mice. . 12:7015-7029. https://doi.org/10.18632/aging.103059
Zhang Q, Zhang Y, Yan M, Zhu K, Su Q, Pan J, Yang M, Zhou D, Tan J, . βig-h3 enhances chondrogenesis via promoting mesenchymal condensation in rat Achilles tendon heterotopic ossification model. . 12:7030-7041. https://doi.org/10.18632/aging.103060
Lu S, Yin X, Wang J, Gu Q, Huang Q, Jin N, Chu D, Xu Z, Liu F, Qian W, . SIRT1 regulates O-GlcNAcylation of tau through OGT. . 12:7042-7055. https://doi.org/10.18632/aging.103062
Long S, Li M, Liu J, Yang Y, Li G, . Identification of immunologic subtype and prognosis of GBM based on TNFSF14 and immune checkpoint gene expression profiling. . 12:7112-7128. https://doi.org/10.18632/aging.103065
Bai M, Niu W, Zhou Y, Gong Y, Lu Y, Yu X, Wei Z, Wu W, Song H, Yu W, Gu B, Cai W, Chu X, . Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility. . 12:7163-7182. https://doi.org/10.18632/aging.103067
Elshaer M, ElManawy AI, Hammad A, Namani A, Wang XJ, Tang X, . Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas. . 12:7183-7206. https://doi.org/10.18632/aging.103068
Hammer A, Ranaie G, Yakubov E, Erbguth F, Holtmannspoetter M, Steiner H, Janssen H, . Dynamics of outcome after aneurysmal subarachnoid hemorrhage. . 12:7207-7217. https://doi.org/10.18632/aging.103069
Li H, Wang A, Gao Q, Wang X, Luo Y, Yang X, Li X, Wang W, Zheng D, Guo X, . Prevalence of somatic-mental multimorbidity and its prospective association with disability among older adults in China. . 12:7218-7231. https://doi.org/10.18632/aging.103070
Li H, Li Z, Pi Y, Chen Y, Mei L, Luo Y, Xie J, Mao X, . MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B. . 12:7248-7261. https://doi.org/10.18632/aging.103073
Yang N, Li Z, Han D, Mi X, Tian M, Liu T, Li Y, He J, Kuang C, Cao Y, Li L, Ni C, Wang JQ, et al, . Autophagy prevents hippocampal α-synuclein oligomerization and early cognitive dysfunction after anesthesia/surgery in aged rats. . 12:7262-7281. https://doi.org/10.18632/aging.103074
Yao K, He L, Gan Y, Liu J, Tang J, Long Z, Tan J, . HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27. . 12:7282-7298. https://doi.org/10.18632/aging.103076
Satirapod C, Wang N, MacDonald JA, Sun M, Woods DC, Tilly JL, . Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging. . 12:7313-7333. https://doi.org/10.18632/aging.103080
Asokan SM, Wang T, Wang M, Lin W, . A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway. . 12:7334-7349. https://doi.org/10.18632/aging.103081
Ou Q, Ma N, Yu Z, Wang R, Hou Y, Wang Z, Chen F, Li W, Bi J, Ma J, Zhang L, Su Q, Huang X, . Nudix hydrolase 1 is a prognostic biomarker in hepatocellular carcinoma. . 12:7363-7379. https://doi.org/10.18632/aging.103083
Cai L, Chao G, Li W, Zhu J, Li F, Qi B, Wei Y, Chen S, Zhou G, Lu X, Xu J, Wu X, Fan G, et al, . Activated CD4+ T cells-derived exosomal miR-142-3p boosts post-ischemic ventricular remodeling by activating myofibroblast. . 12:7380-7396. https://doi.org/10.18632/aging.103084
Li L, Yi C, Xia W, Huang B, Chen S, Zhong J, Fang X, Yang L, Xin H, Zheng SS, Chong BH, Fu Y, Chen C, et al, . c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis. . 12:7397-7410. https://doi.org/10.18632/aging.103086
Liu Y, Bai H, Guo F, Thai PN, Luo X, Zhang P, Yang C, Feng X, Zhu D, Guo J, Liang P, Xu Z, Yang H, et al, . PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells. . 12:7411-7430. https://doi.org/10.18632/aging.103088
Chen ACH, Peng Q, Fong SW, Yeung WSB, Lee YL, . Sirt1 is regulated by miR-135a and involved in DNA damage repair during mouse cellular reprogramming. . 12:7431-7447. https://doi.org/10.18632/aging.103090
Cheng G, Yu Y, Wang L, Pan Q, . Overexpression of LINC00160 predicts poor outcome and promotes progression of clear cell renal cell carcinoma. . 12:7448-7464. https://doi.org/10.18632/aging.103091
Mou J, Hu T, Wang Z, Chen W, Wang Y, Zhang W, . ATM gene polymorphisms are associated with poor prognosis of non-small cell lung cancer receiving radiation therapy. . 12:7465-7479. https://doi.org/10.18632/aging.103094
Mi B, Li Q, Li T, Liu G, Sai J, . High miR-31-5p expression promotes colon adenocarcinoma progression by targeting TNS1. . 12:7480-7490. https://doi.org/10.18632/aging.103096
Zhao T, Liu X, Sun Z, Zhang J, Zhang X, Wang C, Geng R, Zheng T, Li B, Zheng QY, . RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model. . 12:7491-7510. https://doi.org/10.18632/aging.103103
Lu Y, Jan Y, Ko B, Liang S, Chen L, Wu C, Chin C, Kuo C, Yet S, Liou J, . Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia. . 12:7511-7533. https://doi.org/10.18632/aging.103104
Bai Z, Liu W, He D, Wang Y, Yi W, Luo C, Shen J, Hu Z, . Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cells. . 12:7534-7548. https://doi.org/10.18632/aging.103109
Zhou J, Lei J, Wang J, Lian C, Hua L, Yang L, Wu S, . Validation of the 8th edition of the American Joint Committee on Cancer Pathological Prognostic Staging for young breast cancer patients. . 12:7549-7560. https://doi.org/10.18632/aging.103111
Zucchelli A, Marengoni A, Rizzuto D, Calderón-Larrañaga A, Zucchelli M, Bernabei R, Onder G, Fratiglioni L, Vetrano DL, . Using a genetic algorithm to derive a highly predictive and context-specific frailty index. . 12:7561-7575. https://doi.org/10.18632/aging.103118
Kordowitzki P, Hamdi M, Derevyanko A, Rizos D, Blasco M, . The effect of rapamycin on bovine oocyte maturation success and metaphase telomere length maintenance. . 12:7576-7584. https://doi.org/10.18632/aging.103126
Giuseppe Stefano Netti, Giuseppe Lucarelli, Federica Spadaccino, Giuseppe Castellano, Margherita Gigante, Chiara Divella, Maria Teresa Rocchetti, Federica Rascio, Vito Mancini, Giovanni Stallone, Giuseppe Carrieri, Loreto Gesualdo, Michele Battaglia, Elena Ranieri,
Netti GS, Lucarelli G, Spadaccino F, Castellano G, Gigante M, Divella C, Rocchetti MT, Rascio F, Mancini V, Stallone G, Carrieri G, Gesualdo L, Battaglia M, et al, . PTX3 modulates the immunoflogosis in tumor microenvironment and is a prognostic factor for patients with clear cell renal cell carcinoma. . 12:7585-7602. https://doi.org/10.18632/aging.103169
Sofia Annis, Zoë Fleischmann, Robert Logan, Zachary Mullin-Bernstein, Melissa Franco, Josefin Saürich, Jonathan L. Tilly, Dori C. Woods, Konstantin Khrapko,