Research Paper Volume 14, Issue 12 pp 5271—5291
Molecular subtypes, prognostic and immunotherapeutic relevant gene signatures mediated by DNA methylation regulators in hepatocellular carcinoma
Figure 3. Characteristics of distinct DNA methylation regulator-related molecular subtypes. (A) The abundance of 28 tumor microenvironment cell infiltration among three molecular subtypes. (B, C) GSVA enrichment showing the activation states of biological pathways in distinct molecular subtypes. (D) The Venn diagram showing 1037 overlapping differentially expressed genes (DEGs) between three DNA methylation regulator-related molecular subtypes. (E) GO functional enrichment analyses for 1037 overlapping differentially expressed genes. All data analyses were based on the TCGA-LIHC cohort. Neg, negative; Pos, positive; Ns, not significant. *P < 0.05; **P < 0.01; ***P < 0.001.