Research Paper Volume 14, Issue 19 pp 7959—7971

Figure 3. APEX1 modulates HCC cell proliferation, migration, invasion, apoptosis and cell cycle distribution in vitro. (A, B) The efficiency of transfection of sh-APEX1 was detected by qRT-PCR and Western blot assays. (C–E) CCK-8 (C), colony formation (D) and EdU assays (E) were performed to evaluate the effect of APEX1 on the proliferation of HCC cells. (F, G) Wound healing (F) and Transwell assays (G) were performed to evaluate the migration and invasion abilities of HCC cells. (H, I) Flow cytometry was performed to evaluate apoptosis (H) and cell cycle distribution (I). ^*P < 0.05 vs. sh-Ctrl.