Meeting Report Volume 11, Issue 22 pp 9971—9981
Latest advances in aging research and drug discovery
- 1 Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
- 2 Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
- 3 Institute of Neuropathology, University of Zurich, Zurich, Switzerland
- 4 Max Planck Institute for Biology of Ageing, Cologne, Germany
- 5 Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany
- 6 Department of Medicine, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- 7 Arctoris, Oxford, UK
- 8 Gordian Biotechnology, San Francisco, CA 94107, USA
- 9 European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, University of Groningen, AD Groningen, The Netherlands
- 10 Program in Metabolic Biology, Nutritional Sciences and Toxicology, University of California, Berkeley, CA 94720, USA
- 11 SENS Research Foundation, Mountain View, CA 94041, USA
- 12 Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland
- 13 School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
- 14 Haut.AI, Tallinn, Estonia
- 15 Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
- 16 Molecule, Basel, Switzerland
- 17 Roswell Park Comprehensive Cancer Center and Genome Protection, Inc., Buffalo, NY 14203, USA
- 18 Institute for Genetics and CECAD Research Center, University of Cologne, Cologne, Germany
- 19 Department of Pathology, School of Medicine, University of Washington, Seattle, WA 98195, USA
- 20 Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
- 21 Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden
- 22 Institute of Biotechnology, University of Helsinki, Helsinki, Finland
- 23 Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University Singapore, Singapore
- 24 Centre for Healthy Ageing, National University Healthy System, Singapore
- 25 Buck Institute for Research on Aging, Novato, CA 94945, USA
- 26 Frost and Sullivan, Frankfurt am Main, Germany
- 27 Molecular Neurobiology, German Cancer Research Center, Heidelberg, Germany
- 28 Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia
- 29 Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Russia
- 30 Moscow Institute of Physics and Technology, Dolgoprudny, Russia
- 31 Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Rockville, MD 20850, USA
- 32 Repair Biotechnologies, Inc., Syracuse, NY 13210, USA
- 33 Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge CB2 0XY, UK
- 34 UK Dementia Research Institute, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK
- 35 Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia
Received: October 30, 2019 Accepted: November 9, 2019 Published: November 21, 2019
https://doi.org/10.18632/aging.102487How to Cite
Copyright © 2019 Bakula et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to treat age-associated diseases. The field of aging research is rapidly expanding with multiple advances transpiring in many previously disconnected areas. Several major pharmaceutical, biotechnology, and consumer companies made aging research a priority and are building internal expertise, integrating aging research into traditional business models and exploring new go-to-market strategies. Many of these efforts are spearheaded by the latest advances in artificial intelligence, namely deep learning, including generative and reinforcement learning. To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled “Aging Research and Drug Discovery (ARDD)” held in the capital of the pharmaceutical industry, Basel, Switzerland (