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2024 Press Releases

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The Beginning of Becoming a Human: A Review

05-09-2024

“Debates on when human life begins are rooted deep in philosophical history. However, until recently they have been limited by the state of technology.”

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BUFFALO, NY- May 9, 2024 – A new review paper was published in advance by Aging (listed by MEDLINE/PubMed as "Aging …

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Association Between Neighborhood Deprivation and DNA Methylation in an Autopsy Cohort

05-08-2024

“[...] our study identified one CpG site (cg26514961, PLXNC1 gene) that was significantly associated with neighborhood deprivation in brain tissue.”

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BUFFALO, NY- May 8, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …

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Association of Inflammatory and Metabolic Biomarkers and Accelerated Aging in Cardiac Catheterization Patients

05-07-2024

“[...] this study is an initial examination of the associations between epigenetic and transcriptomic aging biomarkers and novel NMR lipoprotein biomarkers.”

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BUFFALO, NY- May 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging …

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A Novel Deep Proteomic Approach Unveils Molecular Signatures Affected by Aging and Resistance Training

05-01-2024

“Resistance training can reverse certain aspects of skeletal muscle aging.”

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BUFFALO, NY- May 1, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, “A novel …

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Cover Paper: Senescent Characteristics of Human Corneal Endothelial Cells Upon UV-A Exposure

04-30-2024

“[...] these findings may help to advance our understanding of the pathogenesis of corneal endothelial disease and may lead to the discovery of new therapies targeting senescent cells.”

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BUFFALO, NY- April 30, 2024 – A new research paper was published on the cover of Aging

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Identifying Proteins Causally Related to COVID-19, Healthspan and Lifespan

04-24-2024

“[...] we identified multiple proteins affecting COVID-19 and aging.”

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BUFFALO, NY- April 24, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 7, entitled, “Using …

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The Coupling Between Healthspan and Lifespan in Caenorhabditis Depends on…

04-23-2024

“The ultimate goal of exploiting model organisms to screen for anti-aging interventions is to identify treatments that might translate to healthy lifespan extension in humans.”

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BUFFALO, NY- April 23, 2024 – A new research paper was published in Aging (listed by …

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Longevity & Aging Series: Season 2 Premiere Episode

04-22-2024

The Longevity & Aging Series launched its second season with a premiere episode featuring Dr. Irina Conboy and Xiaoyue (Serafina) Mei from the University of California, Berkeley.

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BUFFALO, NY- April 22, 2024 – The Longevity & Aging Series is an enlightening and …

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The Impact of Ketogenic Diets on Cognitive Behavior, Motor Function, and Blood Lipids

04-17-2024

“[...] intermittent ketogenic diet (IKD) or ketogenic diet (KD) intervention did not improve measures of cognitive or motor behavior in TgF344-AD rats; however, both IKD and KD positively impacted circulating lipids.”

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BUFFALO, NY- April 17, 2024 – A new research paper …

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Cover Paper: Evidence of a Pan-tissue Decline in Stemness During Human Aging

04-15-2024

“[...] as far as we know, we are the first to provide evidence of [stem cell depletion in aging] in a pan-tissue manner.”

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BUFFALO, NY- April 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …

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Geraniol Attenuates Oxidative Stress and Cognitive Impairment in Mouse Aging Model

04-10-2024

“Our data demonstrated, for the first time, the antioxidant activity of geraniol and its function to attenuate brain hippocampus injury induced in vivo by D-galactose.”

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BUFFALO, NY- April 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as …

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CMS121 Mitigates Aging-related Obesity and Metabolic Dysfunction

04-09-2024

“[...] CMS121 applicability could be expanded from a geroneuroprotector drug to a metabolic drug [...]”

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BUFFALO, NY- April 9, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, …

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Does Methylene Blue or Mitoquinone Improve Skeletal Aging?

04-03-2024

“[...] long-term administration of MB or MitoQ did not have an effect on skeletal morphology during the aging process [...]”

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BUFFALO, NY- April 3, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …

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Altered Brain Morphology and Functional Connectivity in Postmenopausal Women

04-01-2024

“[...] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related symptoms caused by the lower sex hormone levels.”

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BUFFALO, NY- April 1, 2024 – A new research paper was published on the cover of Aging (listed by …

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Chlorogenic Acid Prevents Ovariectomized-induced Bone Loss

03-26-2024

“[...] chlorogenic acid appears to be a promising candidate for the management of osteoporosis.”

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BUFFALO, NY- March 26, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5

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FoxO6-mediated ApoC3 Upregulation Promotes Hepatic Steatosis and Hyperlipidemia in HFD Aged Rats

03-20-2024

“This discovery unveils a potential novel molecular target for therapeutic strategies against hepatic steatosis during the aging process [...]”

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BUFFALO, NY- March 20, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …

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PR55α-controlled PP2A Inhibits p16 Expression and Blocks Cellular Senescence Induction

03-19-2024

“Our results show that PR55α specifically reduces p16 expression [...]”

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BUFFALO, NY- March 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, “PR55α-contro…

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Age Prediction Models in the Human Brain: Genome-wide Transcriptome Profiling and Development

03-15-2024

“Our approach identified genes that were previously implicated in aging, as well as new ones that may warrant further investigation.”

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BUFFALO, NY- March 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …

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Transcriptomic Modulation of Alzheimer’s Disease by Activated Protein C Using Single-Cell RNA-Seq

03-13-2024

“We believe our study utilizing Single-Cell RNA sequencing will provide additional rationale towards the effects on APC treatment observed in previous studies on 5xFAD AD mice.”

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BUFFALO, NY- March 13, 2024 – A new research paper was published in Aging (listed by …

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Association of Prenatal Vitamins and Metals With Epigenetic Aging at Birth and in Childhood

03-12-2024

“[...] our findings support the hypothesis that the intrauterine environment, particularly essential and non-essential metals, affect epigenetic aging biomarkers across the life course.”

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BUFFALO, NY- March 12, 2024 – A new research paper was published in Aging (listed by …

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Aging at AACR Annual Meeting 2024

03-11-2024

Aging is proud to participate at the American Association for Cancer Research (AACR) Annual Meeting 2024, which convenes April 5-10 in San Diego, California.

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BUFFALO, NY- March 11, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a …

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A Longitudinal Study on Dasatinib, Quercetin, and Fisetin Senolytic Interventions

03-06-2024

“[...] our findings underscore the imperative for additional markers to gauge the physiological impact of senolytic treatments [...]”

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BUFFALO, NY- March 6, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …

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A Call for Standardization of Controls in Lifespan Studies

03-05-2024

“[...] we posit that the majority of results in biology of aging may be irrelevant to the fundamental aim of this field and must be acknowledged appropriately.”

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BUFFALO, NY- March 5, 2024 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as …

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Mapping the Core Senescence Phenotype of Human Colon Fibroblasts

02-29-2024

“[...] despite the impact of aging on colon health and colon cancer, an atlas of the SASP produced by colon fibroblasts has not been established.”

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BUFFALO, NY- February 29, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …

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Prognostic Model Development and Molecular Subtypes Identification in Bladder Urothelial Cancer

02-28-2024

“Our study introduces an oxidative stress-based prognostic model for bladder cancer, offering insights into personalized therapy.”

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BUFFALO, NY- February 28, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …

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The Anti-aging Effect of Vitamin D and its Receptor in Drosophila Midgut

02-27-2024

“Our study demonstrated that the VitD/VDR [vitamin D/vitamin D receptor] pathway is required for intestinal homeostasis during normal differentiation and aging.”

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BUFFALO, NY- February 27, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as …

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Disruption of Mitochondrial Unfolded Protein Response Results in Shortening of Telomeres in Mouse Oocytes and Somatic Cells

02-21-2024

“[...] our findings provide a preliminary understanding of how mitochondrial and telomeric aging mechanisms may interact to accelerate reproductive and somatic aging.”

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BUFFALO, NY- February 21, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed …

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New Study: Defining the Progeria Phenome

02-20-2024

“In sum, we have defined what a premature aging disease is and developed tools to allow diagnostics of patients and disease population.”

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BUFFALO, NY- February 20, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …

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GV1001 Reduces Neurodegeneration and Prolongs Lifespan in Mouse Model of Alzheimer’s Disease

02-15-2024

“[...] accelerated aging and Alzheimer’s disease are closely related, and this study confirmed that GV1001 has multiple anti-aging effects.”

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BUFFALO, NY- February 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging …

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IL-17 Promotes IL-18 Production in Osteoarthritis Synovial Fibroblasts Via…

02-13-2024

“This study provides novel insights into the pathogenesis of OA and suggests a potential therapeutic target in OA treatment.” 

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BUFFALO, NY- February 13, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by …

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PROX1/α-SMA Correlated With Colorectal Cancer Progression, Poor Outcomes and Therapeutic Resistance

02-07-2024

“The findings validate the combined PROX1/α-SMA gene set as a prospective prognostic biomarker and a central regulator in CRC progression and its TME.”

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BUFFALO, NY- February 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …

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Epigenetic Drift Underlies Epigenetic Clock Signals, but…

02-06-2024

“In this study, we report an approach for spatially resolving genomic patterns of DNA methylation disorder [...]”

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BUFFALO, NY- February 6, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of …

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Prognostic Significance of Senescence-related TME Genes in Head and Neck Squamous Cell Carcinoma

01-31-2024

“These findings provided evidence for the role of senescence in the tumor microenvironment [...]”

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BUFFALO, NY- January 31, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Vo…

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XRCC1: A Potential Prognostic and Immunological Biomarker in Low-Grade Gliomas

01-30-2024

“We conducted a comprehensive investigation into the potential of XRCC1 as a valuable diagnostic and prognostic indicator in diverse cancer types."

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BUFFALO, NY- January 30, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" …

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Targeting FSP1 Regulates Iron Homeostasis in Drug-tolerant Persister Head and Neck Cancer Cells

01-24-2024

“Targeting FSP1 is suggested as a new approach in the paradigm shift of treating HNSCC.”

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BUFFALO, NY- January 24, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, …

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Systematic Analysis of the Prognostic Value and Immunological Function of LTBR in Cancer

01-23-2024

“[...] we identified LTBR as a potential target for cancer immunotherapy and a marker of immune infiltration and poor prognosis.”

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BUFFALO, NY- January 23, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" …

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Aberrant RBMX Expression Relevant for Cancer Prognosis and Immunotherapy Response

01-17-2024

“In the future, targeting of RBMX may be a novel method in cancer therapy.”

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BUFFALO, NY- January 17, 2024 – A new research paper was published inAging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, “Aberran…

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Effects of Resveratrol on Circadian Clock Gene Expression in Young and Older Human Cells

01-15-2024

“This study reflects transdisciplinary efforts to link aging and circadian biology in human-derived tissues, which is an understudied area of biology.”

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BUFFALO, NY- January 15, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as …

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Clonal Hematopoiesis and Its Impact on Aging, Cancer, and Patient Care

01-10-2024

“Understanding the influence of prior treatments on CH [clonal hematopoiesis] dynamics is crucial for comprehending the intricate interplay between therapy, aging, and cancer.” 

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BUFFALO, NY- January 10, 2024 – A new editorial paper was published in Aging (listed by …

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Systemic Changes Induced by ASCOT in Plasma Proteome of Women With Impaired Ovarian Reserves

01-09-2024

“Identifying plasma proteins that regenerate aged or damaged ovaries could lead to more effective, targeted and/or preventive therapies for patients.”

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BUFFALO, NY- January 9, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany …

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Mapping the Gene Network That Regulates the Glycan Clock of Ageing

01-03-2024

“[...] we were able to confirm the functional role of three genes (MANBA, TNFRSF13B and EEF1A1) in the IgG galactosylation pathway [...]” 

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BUFFALO, NY- January 3, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and …

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Age-related Alterations in the Oscillatory Dynamics Serving Verbal Working Memory

01-02-2024

“[...] we discuss the implications of these novel findings on our understanding of how healthy aging affects verbal working memory processing.”

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BUFFALO, NY- January 2, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging …

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