Interviews with Outstanding Authors
Novel TRKB Agonists Activate TRKB and Downstream ERK and AKT Signaling
Dr. Ya-Jen Chiu from the Department of Life Science at National Taiwan Normal University in Taipei, discusses a paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”
Lotus Germ Extract Rejuvenates Fibroblasts Via Restoration of Disrupted Proteostasis
Dr. Takushi Namba, Associate Professor at Kochi University in Japan, discusses a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 19, entitled, “Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy.”
Psychological Factors Contribute to Biological Aging in Chinese Older Adults
Fedor Galkin, Scientific Director at Deep Longevity, Inc. in Hong Kong, discusses a research paper he co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 18, entitled, “Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults.”
Longevity & Aging Series Episode 5: Dr. Amit Sharma
Dr. Amit Sharma, Group Lead from SENS Research Foundation, discusses a research paper he co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells.”
Epigenetic Clocks Association with Perceived Discrimination, Depressive Symptoms
Dr. May Beydoun from the Laboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, in Baltimore, MD, discusses a research paper she co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 13, entitled, “Epigenetic clocks and their association with trajectories in perceived discrimination and depressive symptoms among US middle-aged and older adults.”
Longevity & Aging Series Episode 4: Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo
In episode 4 of the Longevity & Aging Series, Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo discuss a research paper they co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.”
Longevity & Aging Series Episode 3: Dr. Steve Horvath - Epigenetic Clocks
In episode 3 of the Longevity & Aging Series, Dr. Steve Horvath, Professor of Human Genetics and Biostatistics at UCLA, and Principal Investigator at Altos Labs, discusses the evolution of aging research and epigenetic clocks with host Dr. Brian Chen.
Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath
Longevity & Aging Series Episode 2: Dr. Steve Horvath’s Special Collection in Aging
In the second installment of the Longevity & Aging Series, Dr. Steve Horvath revisits papers he co-authored that were published by Aging (Aging-US) and featured as a special collection of his research.
Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath
Biological Age in Diabetes and Precision Medicine
Dr. Cristina Aguayo-Mazzucato from Beta Cell Aging Lab, Joslin Diabetes Center, Harvard Medical School, discusses an editorial she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 11, entitled, “Biological age in diabetes and precision medicine.”
Facial Expression Recognition Predicts Neuropsychiatric Symptoms of Dementia
Dr. Liang-Kung Chen from the National Yang-Ming Chiao-Tung University, Taipei, Taiwan details a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 3, entitled, “Predicting neuropsychiatric symptoms of persons with dementia in a day care center using a facial expression recognition system.”
Longevity & Aging Series Episode 1: Dr. Alex Zhavoronkov and Dr. Frank Pun
In the first episode of the Longevity & Aging Series, Drs. Alex Zhavoronkov and Frank Pun discuss, in detail, their recently published research paper, “Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine.”
The puzzling interplay between p53 and Sp1
Dr. Ariella Oppenheim from the Department of Hematology, Hebrew University Faculty of Medicine, Jerusalem, Israel, details an editorial she co-authored that was published by Aging (Aging-US) in Volume 9, Issue 5, entitled, “The puzzling interplay between p53 and Sp1.”
DOI - https://doi.org/10.18632/aging.101238 (PDF download)
Full text - https://www.aging-us.com/article/101238
DNA Methylation-based Measures of Biological Age
Aging-US published "DNA methylation-based measures of biological age: meta-analysis predicting time to death" in 2016, which reported that estimates of biological age based on DNA methylation patterns, often referred to as "epigenetic age", "DNAm age", have been shown to be robust biomarkers of age in humans.
Epigenetic Age of the Pre-frontal Cortex
Aging-US published "Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning" in 2015, which reported that there is an urgent need to develop molecular biomarkers of brain age in order to advance our understanding of age related neurodegeneration.
Iron: An Underrated Factor in Aging
Dennis Mangan from MTOR LLC in Bakersfield, California details his theory article published by Aging (Aging-US), entitled, “Iron: an underrated factor in aging.”
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2022 Interviews
Novel TRKB Agonists Activate TRKB and Downstream ERK and AKT Signaling
Dr. Ya-Jen Chiu from the Department of Life Science at National Taiwan Normal University in Taipei, discusses a paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”
Lotus Germ Extract Rejuvenates Fibroblasts Via Restoration of Disrupted Proteostasis
Dr. Takushi Namba, Associate Professor at Kochi University in Japan, discusses a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 19, entitled, “Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy.”
Psychological Factors Contribute to Biological Aging in Chinese Older Adults
Fedor Galkin, Scientific Director at Deep Longevity, Inc. in Hong Kong, discusses a research paper he co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 18, entitled, “Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults.”
Longevity & Aging Series Episode 5: Dr. Amit Sharma
Dr. Amit Sharma, Group Lead from SENS Research Foundation, discusses a research paper he co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells.”
Epigenetic Clocks Association with Perceived Discrimination, Depressive Symptoms
Dr. May Beydoun from the Laboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, in Baltimore, MD, discusses a research paper she co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 13, entitled, “Epigenetic clocks and their association with trajectories in perceived discrimination and depressive symptoms among US middle-aged and older adults.”
Longevity & Aging Series Episode 4: Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo
In episode 4 of the Longevity & Aging Series, Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo discuss a research paper they co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.”
Longevity & Aging Series Episode 3: Dr. Steve Horvath - Epigenetic Clocks
In episode 3 of the Longevity & Aging Series, Dr. Steve Horvath, Professor of Human Genetics and Biostatistics at UCLA, and Principal Investigator at Altos Labs, discusses the evolution of aging research and epigenetic clocks with host Dr. Brian Chen.
Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath
Longevity & Aging Series Episode 2: Dr. Steve Horvath’s Special Collection in Aging
In the second installment of the Longevity & Aging Series, Dr. Steve Horvath revisits papers he co-authored that were published by Aging (Aging-US) and featured as a special collection of his research.
Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath
Biological Age in Diabetes and Precision Medicine
Dr. Cristina Aguayo-Mazzucato from Beta Cell Aging Lab, Joslin Diabetes Center, Harvard Medical School, discusses an editorial she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 11, entitled, “Biological age in diabetes and precision medicine.”
Facial Expression Recognition Predicts Neuropsychiatric Symptoms of Dementia
Dr. Liang-Kung Chen from the National Yang-Ming Chiao-Tung University, Taipei, Taiwan details a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 3, entitled, “Predicting neuropsychiatric symptoms of persons with dementia in a day care center using a facial expression recognition system.”
Longevity & Aging Series Episode 1: Dr. Alex Zhavoronkov and Dr. Frank Pun
In the first episode of the Longevity & Aging Series, Drs. Alex Zhavoronkov and Frank Pun discuss, in detail, their recently published research paper, “Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine.”
The puzzling interplay between p53 and Sp1
Dr. Ariella Oppenheim from the Department of Hematology, Hebrew University Faculty of Medicine, Jerusalem, Israel, details an editorial she co-authored that was published by Aging (Aging-US) in Volume 9, Issue 5, entitled, “The puzzling interplay between p53 and Sp1.”
DOI - https://doi.org/10.18632/aging.101238 (PDF download)
Full text - https://www.aging-us.com/article/101238
DNA Methylation-based Measures of Biological Age
Aging-US published "DNA methylation-based measures of biological age: meta-analysis predicting time to death" in 2016, which reported that estimates of biological age based on DNA methylation patterns, often referred to as "epigenetic age", "DNAm age", have been shown to be robust biomarkers of age in humans.
Epigenetic Age of the Pre-frontal Cortex
Aging-US published "Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning" in 2015, which reported that there is an urgent need to develop molecular biomarkers of brain age in order to advance our understanding of age related neurodegeneration.
Iron: An Underrated Factor in Aging
Dennis Mangan from MTOR LLC in Bakersfield, California details his theory article published by Aging (Aging-US), entitled, “Iron: an underrated factor in aging.”