Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 11, Issue 4

28 February, 2019
pp 1070—1316

About the Cover

The cover features Figure 5 "Pathway analysis for age and poverty" from Noren Hooten.

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Editorials

Tackling anti-coagulation under-prescription in the elderly

Ameenathul M. Fawzy, Tse-Fan Chao, Gregory Y.H. Lip,

https://doi.org/10.18632/aging.101809 pp 1070—1072

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Lipid analysis in an aging population

Vincent A. Pallazola, Vasanth Sathiyakumar, Seth S. Martin,

https://doi.org/10.18632/aging.101811 pp 1073—1074

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New avenues in cardio-oncology

Valentina Sala, Mingchuan Li, Alessandra Ghigo,

https://doi.org/10.18632/aging.101817 pp 1075—1076

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Aβ oligomers: role at the synapse

Daniela Puzzo,

https://doi.org/10.18632/aging.101818 pp 1077—1078

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RhoA in aneurysmal subarachnoid hemorrhage

Juan Ureña, María del Carmen González-Montelongo, Francisco Murillo-Cabezas,

https://doi.org/10.18632/aging.101819 pp 1079—1080

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Parkinson’s disease as a systemic pathology

Mario Ezquerra, María-José Martí, Rubén Fernández-Santiago,

https://doi.org/10.18632/aging.101824 pp 1081—1082

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Endothelial cells dictate cardiac fuel source

Jacqueline Taylor, Andreas Fischer,

https://doi.org/10.18632/aging.101825 pp 1083—1084

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Aortic stenosis: what is the role of aging processes?

Nancy Côté, Philippe Pibarot, Marie-Annick Clavel,

https://doi.org/10.18632/aging.101826 pp 1085—1086

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Potential role of miRNA-140 in Alzheimer’s disease

Rumana Akhter, Lynn M. Bekris,

https://doi.org/10.18632/aging.101827 pp 1087—1088

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Research Papers

MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

Ying Zhu, Tianrui Yang, Jinlan Duan, Ninghui Mu, Tong Zhang,

https://doi.org/10.18632/aging.101766 pp 1089—1109

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The ubiquitin ligase KBTBD8 regulates PKM1 levels via Erk1/2 and Aurora A to ensure oocyte quality

Yan-Ru Li, Rui-Rui Peng, Wen-Yi Gao, Peng Liu, Liang-Jian Chen, Xiao-Lan Zhang, Na-Na Zhang, Yang Wang, Lei Du, Feng-Yu Zhu, Li-Li Wang, Cong-Rong Li, Wen-Tao Zeng, Jian-Min Li, Fan Hu, Dong Zhang, Zhi-Xia Yang,

https://doi.org/10.18632/aging.101802 pp 1110—1128

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Stem cell-derived extracellular vesicles for myocardial infarction: a meta-analysis of controlled animal studies

Lihong Yang, Jialu Zhu, Cong Zhang, Juntao Wang, Fengyang Yue, Xingtai Jia, Hongzhi Liu,

https://doi.org/10.18632/aging.101814 pp 1129—1150

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DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways

Juan Wang, Sayyed Hanif Ullah, Meihe Li, Miao Zhang, Fujun Zhang, Jin Zheng, Xiaofei Yan,

https://doi.org/10.18632/aging.101815 pp 1151—1162

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Alzheimer’s disease as a multistage process: an analysis from a population-based cohort study

Silvan Licher, Kimberly D. van der Willik, Elisabeth J. Vinke, Pinar Yilmaz, Lana Fani, Sanne B. Schagen, M. Arfan Ikram, M. Kamran Ikram,

https://doi.org/10.18632/aging.101816 pp 1163—1176

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Nutraceutical effects of Emblica officinalis in age-related macular degeneration

Sonali Nashine, Raj Kanodia, Anthony B. Nesburn, Girish Soman, Baruch D. Kuppermann, M. Cristina Kenney,

https://doi.org/10.18632/aging.101820 pp 1177—1188

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Age and poverty status alter the coding and noncoding transcriptome

Nicole Noren Hooten, Michele K. Evans,

https://doi.org/10.18632/aging.101823 pp 1189—1203

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m⁶A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas

Rui-Chao Chai, Fan Wu, Qi-Xue Wang, Shu Zhang, Ke-Nan Zhang, Yu-Qing Liu, Zheng Zhao, Tao Jiang, Yong-Zhi Wang, Chun-Sheng Kang,

https://doi.org/10.18632/aging.101829 pp 1204—1225

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Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis: in vivo and in vitro experiments

Zeyu Li, Yifan Jia, Yang Feng, Ruixia Cui, Runchen Miao, Xing Zhang, Kai Qu, Chang Liu, Jingyao Zhang,

https://doi.org/10.18632/aging.101831 pp 1226—1239

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Epigenetic signature: implications for mitochondrial quality control in human aging

Patrizia D’Aquila, Alberto Montesanto, Francesco De Rango, Francesco Guarasci, Giuseppe Passarino, Dina Bellizzi,

https://doi.org/10.18632/aging.101832 pp 1240—1251

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Pleiotropic effect of common PHOX2B variants in Hirschsprung disease and neuroblastoma

Jinglu Zhao, Yun Zhu, Xiaoli Xie, Yuxiao Yao, Jiao Zhang, Ruizhong Zhang, Lihua Huang, Jiwen Cheng, Huimin Xia, Jing He, Yan Zhang,

https://doi.org/10.18632/aging.101834 pp 1252—1261

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Longitudinal plasma metabolomics of aging and sex

Burcu F. Darst, Rebecca L. Koscik, Kirk J. Hogan, Sterling C. Johnson, Corinne D. Engelman,

https://doi.org/10.18632/aging.101837 pp 1262—1282

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Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction

Dae Hyun Kim, Min Hi Park, Sugyeong Ha, Eun Jin Bang, Yujeong Lee, A Kyoung Lee, Jaewon Lee, Byung Pal Yu, Hae Young Chung,

https://doi.org/10.18632/aging.101838 pp 1283—1304

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Research Perspective

Towards a more precise and individualized assessment of breast cancer risk

Marie E. Wood, Nicholas H. Farina, Thomas P. Ahern, Melissa E. Cuke, Janet L. Stein, Gary S. Stein, Jane B. Lian,

https://doi.org/10.18632/aging.101803 pp 1305—1316

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Featured Nobel Articles

Volume 11, Issue 4

About the Cover

Editorials

Ameenathul M. Fawzy, Tse-Fan Chao, Gregory Y.H. Lip,

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Vincent A. Pallazola, Vasanth Sathiyakumar, Seth S. Martin,

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Valentina Sala, Mingchuan Li, Alessandra Ghigo,

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Daniela Puzzo,

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Juan Ureña, María del Carmen González-Montelongo, Francisco Murillo-Cabezas,

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Mario Ezquerra, María-José Martí, Rubén Fernández-Santiago,

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Jacqueline Taylor, Andreas Fischer,

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Nancy Côté, Philippe Pibarot, Marie-Annick Clavel,

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Rumana Akhter, Lynn M. Bekris,

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Research Papers

Ying Zhu, Tianrui Yang, Jinlan Duan, Ninghui Mu, Tong Zhang,

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Yan-Ru Li, Rui-Rui Peng, Wen-Yi Gao, Peng Liu, Liang-Jian Chen, Xiao-Lan Zhang, Na-Na Zhang, Yang Wang, Lei Du, Feng-Yu Zhu, Li-Li Wang, Cong-Rong Li, Wen-Tao Zeng, Jian-Min Li, Fan Hu, Dong Zhang, Zhi-Xia Yang,

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Lihong Yang, Jialu Zhu, Cong Zhang, Juntao Wang, Fengyang Yue, Xingtai Jia, Hongzhi Liu,

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Juan Wang, Sayyed Hanif Ullah, Meihe Li, Miao Zhang, Fujun Zhang, Jin Zheng, Xiaofei Yan,

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Silvan Licher, Kimberly D. van der Willik, Elisabeth J. Vinke, Pinar Yilmaz, Lana Fani, Sanne B. Schagen, M. Arfan Ikram, M. Kamran Ikram,

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Sonali Nashine, Raj Kanodia, Anthony B. Nesburn, Girish Soman, Baruch D. Kuppermann, M. Cristina Kenney,

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Nicole Noren Hooten, Michele K. Evans,

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Rui-Chao Chai, Fan Wu, Qi-Xue Wang, Shu Zhang, Ke-Nan Zhang, Yu-Qing Liu, Zheng Zhao, Tao Jiang, Yong-Zhi Wang, Chun-Sheng Kang,

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Zeyu Li, Yifan Jia, Yang Feng, Ruixia Cui, Runchen Miao, Xing Zhang, Kai Qu, Chang Liu, Jingyao Zhang,

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Patrizia D’Aquila, Alberto Montesanto, Francesco De Rango, Francesco Guarasci, Giuseppe Passarino, Dina Bellizzi,

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