Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 4, Issue 1

January 2012
pp 1—73

Explore This Issue

Editorial

Starting 2012: Sod2, DGAT1, p53, SPARC, QTL and reprogramming in aging

https://doi.org/10.18632/aging.100429 pp 1

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Editorial Interview

Interview with Michael Ristow

https://doi.org/10.18632/aging.100430 pp 2

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Research Papers

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

Michael C. Velarde, James M. Flynn, Nicholas U. Day, Simon Melov, Judith Campisi,

https://doi.org/10.18632/aging.100423 pp 3—12

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Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

Ryan S. Streeper, Carrie A. Grueter, Nathan Salomonis, Sylvaine Cases, Malin C. Levin, Suneil K. Koliwad, Ping Zhou, Matthew D. Hirschey, Eric Verdin, Robert V. Farese Jr.,

https://doi.org/10.18632/aging.100424 pp 13—27

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TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells

Serena Altilia, Aurelia Santoro, Davide Malagoli, Catia Lanzarini, Josué Adolfo Ballesteros Álvarez, Gianluca Galazzo, Donald Carl Porter, Paolina Crocco, Giuseppina Rose, Giuseppe Passarino, Igor Boris Roninson, Claudio Franceschi, Stefano Salvioli,

https://doi.org/10.18632/aging.100425 pp 28—39

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Age-related resistance of skeletal muscle-derived progenitor cells to SPARC may explain a shift from myogenesis to adipogenesis

Serena Katsuyuki Nakamura, Shin-ichi Nakano, Takahiro Miyoshi, Keitaro Yamanouchi, Takashi Matsuwaki, Masugi Nishihara,

https://doi.org/10.18632/aging.100426 pp 40—48

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Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats

Elena E. Korbolina, Ouyna S. Kozhevnikova, Nataliya A. Stefanova, Natalia G. Kolosova,

https://doi.org/10.18632/aging.100427 pp 49—59

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Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency

Seiga Ohmine, Karen A. Squillace, Katherine A. Hartjes, Michael C. Deeds, Adam S. Armstrong, Tayaramma Thatava, Toshie Sakuma, Andre Terzic, Yogish Kudva, Yasuhiro Ikeda,

https://doi.org/10.18632/aging.100428 pp 60—73

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