Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 15, Issue 5

15 March, 2023
pp 1230—1702

About the Cover

The cover features Figure 4 "NT-3 gene transfer improves myelin thickness of peripheral nerves and neuromuscular junction assembly in C57BL/6 mice" from Ozes et al.

Explore This Issue

Editorials

Brain functional networks reorganization for maintaining gait abilities in aging

Amgad Droby, Inbal Maidan, Anat Mirelman,

https://doi.org/10.18632/aging.204556 pp 1230—1231

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Senescence and extracellular vesicles: novel partners in vascular amyloidosis

Meredith Whitehead, Marco Antonazzi, Catherine M. Shanahan,

https://doi.org/10.18632/aging.204571 pp 1232—1234

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Parsing chronological and biological age effects on vaccine responses

Chris P. Verschoor, George A. Kuchel,

https://doi.org/10.18632/aging.204572 pp 1235—1236

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Research Papers

Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells

Amy H. Lee, Deepraj Ghosh, Ivy L. Koh, Michelle R. Dawson,

https://doi.org/10.18632/aging.204539 pp 1237—1256

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Age-related methylation changes in the human sperm epigenome

Laura Bernhardt, Marcus Dittrich, Andreas Prell, Ramya Potabattula, Charis Drummer, Rüdiger Behr, Thomas Hahn, Martin Schorsch, Tobias Müller, Thomas Haaf,

https://doi.org/10.18632/aging.204546 pp 1257—1278

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Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue

Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Tomomi Nakamura, Koki Hashimoto, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami,

https://doi.org/10.18632/aging.204569 pp 1279—1305

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AAV1.NT-3 gene therapy prevents age-related sarcopenia

Burcak Ozes, Lingying Tong, Morgan Myers, Kyle Moss, Alicia Ridgley, Zarife Sahenk,

https://doi.org/10.18632/aging.204577 pp 1306—1329

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Associations between serum total cholesterol level and bone mineral density in older adults

Sheng Hu, Silin Wang, Wenxiong Zhang, Lang Su, Jiayue Ye, Deyuan Zhang, Yang Zhang, Qiang Guo, Dongliang Yu, Jinhua Peng, Jianjun Xu, Yiping Wei,

https://doi.org/10.18632/aging.204514 pp 1330—1342

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Joint effect of THBS2 and VCAN accelerating the poor prognosis of gastric cancer

Long Wang, Li Feng, Linnan Liu, Jing Han, Xue Zhang, Dan Li, Jiayin Liu, Yudong Wang, Jing Zuo, Zhisong Fan,

https://doi.org/10.18632/aging.204520 pp 1343—1357

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Ginkgolide A improves the pleiotropic function and reinforces the neuroprotective effects by mesenchymal stem cell-derived exosomes in 6-OHDA-induced cell model of Parkinson’s disease

William Shao-Tsu Chen, Tzu-Ying Lin, Chia-Hua Kuo, Dennis Jine-Yuan Hsieh, Wei-Wen Kuo, Shih-Chieh Liao, Hui-Chuan Kao, Da-Tong Ju, Yu-Jung Lin, Chih-Yang Huang,

https://doi.org/10.18632/aging.204526 pp 1358—1370

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Identification of m6A regulator-mediated RNA methylation modification patterns and key immune-related genes involved in atrial fibrillation

Peng-Fei Zheng, Sen-Yu Zhou, Chang-Qing Zhong, Zhao-Fen Zheng, Zheng-Yu Liu, Hong-Wei Pan, Jian-Qiang Peng,

https://doi.org/10.18632/aging.204537 pp 1371—1393

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ACSL1, CH25H, GPCPD1, and PLA2G12A as the potential lipid-related diagnostic biomarkers of acute myocardial infarction

Zheng-Yu Liu, Fen Liu, Yan Cao, Shao-Liang Peng, Hong-Wei Pan, Xiu-Qin Hong, Peng-Fei Zheng,

https://doi.org/10.18632/aging.204542 pp 1394—1411

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A novel risk score model based on pyroptosis-related genes for predicting survival and immunogenic landscape in hepatocellular carcinoma

Hongyu Wang, Bo Zhang, Yanan Shang, Fei Chen, Yumei Fan, Ke Tan,

https://doi.org/10.18632/aging.204544 pp 1412—1444

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Identification of GNG7 as a novel biomarker and potential therapeutic target for gastric cancer via bioinformatic analysis and in vitro experiments

Houyu Duan, Biao Chen, Wei Wang, Hesheng Luo,

https://doi.org/10.18632/aging.204545 pp 1445—1474

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Identification MNS1, FRZB, OGN, LUM, SERP1NA3 and FCN3 as the potential immune-related key genes involved in ischaemic cardiomyopathy by random forest and nomogram

Peng-Fei Zheng, Fen Liu, Zhao-Fen Zheng, Hong-Wei Pan, Zheng-Yu Liu,

https://doi.org/10.18632/aging.204547 pp 1475—1495

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Identification of fatty acid metabolism-related clusters and immune infiltration features in hepatocellular carcinoma

Zhixuan Ren, Duan Gao, Yue Luo, Zhenghui Song, Guojing Wu, Na Qi, Aimin Li, Xinhui Liu,

https://doi.org/10.18632/aging.204557 pp 1496—1523

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High expression of TARS is associated with poor prognosis of endometrial cancer

Lihui Si, Lianchang Liu, Ruiqi Yang, Wenxin Li, Xiaohong Xu,

https://doi.org/10.18632/aging.204558 pp 1524—1542

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Identification and integration analysis of a novel prognostic signature associated with cuproptosis-related ferroptosis genes and relevant lncRNA regulatory axis in lung adenocarcinoma

Tianyue Wang, Xinyu Jiang, Ying Lu, Yanmin Ruan, Jiamin Wang,

https://doi.org/10.18632/aging.204561 pp 1543—1563

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A novel circular RNA circRBMS3 regulates proliferation and metastasis of osteosarcoma by targeting miR-424-eIF4B/YRDC axis

Zhe Gong, Panyang Shen, Haitao Wang, Jinjin Zhu, Kaiyu Liang, Kefan Wang, Yunfeng Mi, Shuying Shen, Xiangqian Fang, Gang Liu,

https://doi.org/10.18632/aging.204567 pp 1564—1590

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The disturbance of thyroid-associated hormone and its receptors in brain and blood circulation existed in the early stage of mouse model of Alzheimer’s disease

Bingxiu Ren, Jinxin Ma, Min Tao, Gongwei Jing, Sheng Han, Chengyi Zhou, Xin Wang, Jiaoya Wang,

https://doi.org/10.18632/aging.204570 pp 1591—1602

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Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson’s disease

Lung Chan, Chen-Chih Chung, Ruan-Ching Yu, Chien-Tai Hong,

https://doi.org/10.18632/aging.204575 pp 1603—1614

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Prognostic and clinicopathological significance of prognostic nutritional index (PNI) in patients with oral cancer: a meta-analysis

Menglu Dai, Qijun Sun,

https://doi.org/10.18632/aging.204576 pp 1615—1627

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Integrative analysis to screen novel pyroptosis-related LncRNAs for predicting clinical outcome of glioma and validation in tumor tissue

Shuai Ma, Hongtao Zhao, Fang Wang, Lulu Peng, Heng Zhang, Zaibin Wang, Fan Jiang, Dongtao Zhang, Menglei Yin, Shupeng Li, Jiaming Huang, Zhan Liu, Shengzhong Tao,

https://doi.org/10.18632/aging.204580 pp 1628—1651

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ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis

Po-I Liu, Ya-Jing Jiang, An-Chen Chang, Chang-Lun Huang, Yi-Chin Fong, Jeng-Hung Guo, Chun-Lin Liu, Shih-Wei Wang, Ju-Fang Liu, Sunny Li-Yu Chang, Chih-Hsin Tang,

https://doi.org/10.18632/aging.204581 pp 1652—1667

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Identification and validation of eight estrogen-related genes for predicting prognosis of papillary thyroid cancer

Yu Zeng, Weike Ma, Lijuan Li, Gaojian Zhuang, Guoqing Luo, Hong Zhou, Weijing Hao, Yu Liu, Fengli Guo, Mengran Tian, Xianhui Ruan, Ming Gao, Xiangqian Zheng,

https://doi.org/10.18632/aging.204582 pp 1668—1684

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Signatures of immune cell infiltration for predicting immune escape and immunotherapy in cervical cancer

Fuxing Chen, Lingzhi Shen, Ying Wang, Yaping Chen, Xuejiao Pan, Hui Liang, Hu Yu,

https://doi.org/10.18632/aging.204583 pp 1685—1698

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Correction

Correction for: Integrated transcriptome expression profiling reveals a novel lncRNA associated with l-DOPA-induced dyskinesia in a rat model of Parkinson’s disease

Chun-Lei Han, Yun-Peng Liu, Yun-Peng Sui, Ning Chen, Ting-Ting Du, Ying Jiang, Chen-Jia Guo, Kai-Liang Wang, Qiao Wang, Shi-Ying Fan, Michitomo Shimabukuro, Fan-Gang Meng, Fang Yuan, Jian-Guo Zhang,

https://doi.org/10.18632/aging.204596 pp 1699—1701

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Retraction

Retraction: Downregulation of OIP5-AS1 affects proNGF-induced pancreatic cancer metastasis by inhibiting p75NTR levels

Ang Li, Lei Feng, Xiaoya Niu, Qihui Zeng, Bei Li, Zhen You,

https://doi.org/10.18632/aging.204491 pp 1702

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