Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 9, Issue 12

December 2017
pp 2453—2716

About the Cover

The cover for issue 12 of Aging features Figure 7 "Pathways targeted by palbociclib in SW-13 and NCI-H295R cells" from Hadjadj et al.

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Editorials

Prophylaxis of hereditary breast cancer

Jolien S. de Groot, Paul J. van Diest, Patrick W.B. Derksen,

https://doi.org/10.18632/aging.101342 pp 2453—2454

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Targeting oral cancer epigenome via LSD1

Manish V. Bais,

https://doi.org/10.18632/aging.101343 pp 2455—2456

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CXCL12-CXCR4 axis in feline mammary carcinoma

Fernando Ferreira,

https://doi.org/10.18632/aging.101344 pp 2457—2458

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TC-PTP nuclear trafficking in keratinocytes

Mihwa Kim, Liza D. Morales, Dae Joon Kim,

https://doi.org/10.18632/aging.101345 pp 2459—2460

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Towards specific inhibition of mTORC2

Elizabeth R. Murray, Angus J.M. Cameron,

https://doi.org/10.18632/aging.101346 pp 2461—2462

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Energy balance and the sphingosine-1-phosphate/ceramide axis

Cara Green, Sharon Mitchell, John Speakman,

https://doi.org/10.18632/aging.101347 pp 2463—2464

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CDK1: beyond cell cycle regulation

Hongwei Liao, Fang Ji, Songmin Ying,

https://doi.org/10.18632/aging.101348 pp 2465—2466

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FOXO3 cell resilience gene neighborhood

Timothy A. Donlon, Bradley J. Willcox, Brian J. Morris,

https://doi.org/10.18632/aging.101349 pp 2467—2468

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VCP represses pathological cardiac hypertrophy

Ning Zhou, Shaunrick Stoll, Hongyu Qiu,

https://doi.org/10.18632/aging.101357 pp 2469—2470

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Research Papers

MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung’s disease

Guanglin Chen, Chunxia Du, Ziyang Shen, Lei Peng, Hua Xie, Rujin Zang, Hongxing Li, Yankai Xia, Weibing Tang,

https://doi.org/10.18632/aging.101331 pp 2471—2479

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Transfer of autologous mitochondria from adipose tissue-derived stem cells rescues oocyte quality and infertility in aged mice

Zhen-Bo Wang, Jian-Xiu Hao, Tie-Gang Meng, Lei Guo, Ming-Zhe Dong, Li-Hua Fan, Ying-Chun Ouyang, Guopeng Wang, Qing-Yuan Sun, Xiang-Hong Ou, Yuan-Qing Yao,

https://doi.org/10.18632/aging.101332 pp 2480—2488

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Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

Sarah E. Harris, Valentina Riggio, Louise Evenden, Tamara Gilchrist, Sarah McCafferty, Lee Murphy, Nicola Wrobel, Adele M. Taylor, Janie Corley, Alison Pattie, Simon R. Cox, Carmen Martin-Ruiz, James Prendergast, John M. Starr, Riccardo E. Marioni, Ian J. Deary,

https://doi.org/10.18632/aging.101333 pp 2489—2503

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Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

Luke C. Pilling, Chia-Ling Kuo, Kamil Sicinski, Jone Tamosauskaite, George A. Kuchel, Lorna W. Harries, Pamela Herd, Robert Wallace, Luigi Ferrucci, David Melzer,

https://doi.org/10.18632/aging.101334 pp 2504—2520

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Sexually dimorphic effects of dietary sugar on lifespan, feeding and starvation resistance in Drosophila

Bhakti Chandegra, Jocelyn Lok Yee Tang, Haoyu Chi, Nazif Alic,

https://doi.org/10.18632/aging.101335 pp 2521—2528

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POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions

Yang Yu, Rong Tan, Qian Ren, Boya Gao, Zhejin Sheng, Juanlian Zhang, Xiaoqing Zheng, Ying Jiang, Li Lan, Zhiyong Mao,

https://doi.org/10.18632/aging.101339 pp 2529—2543

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The development of a specific pathogen free (SPF) barrier colony of marmosets (Callithrix jacchus) for aging research

Corinna N. Ross, Steven Austad, Kathy Brasky, Celeste J. Brown, Larry J. Forney, Jonathan A. Gelfond, Robert Lanford, Arlan Richardson, Suzette D. Tardif,

https://doi.org/10.18632/aging.101340 pp 2544—2558

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Central role of the p53 pathway in the noncoding-RNA response to oxidative stress

Paola Fuschi, Matteo Carrara, Christine Voellenkle, Jose Manuel Garcia-Manteiga, Paolo Righini, Biagina Maimone, Elena Sangalli, Francesco Villa, Claudia Specchia, Mario Picozza, Giovanni Nano, Carlo Gaetano, Gaia Spinetti, Annibale A. Puca, Alessandra Magenta, Fabio Martelli,

https://doi.org/10.18632/aging.101341 pp 2559—2586

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Mitogen-activated protein kinases, Fus3 and Kss1, regulate chronological lifespan in yeast

Maneesha Aluru, Tori McKinney, Anne-Kathryn L. Venero, Shilpa Choudhury, Matthew Torres,

https://doi.org/10.18632/aging.101350 pp 2587—2609

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Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy

Bela Ozsvari, Gloria Bonuccelli, Rosa Sanchez-Alvarez, Richard Foster, Federica Sotgia, Michael P. Lisanti,

https://doi.org/10.18632/aging.101351 pp 2610—2628

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Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort

Miao Jiang, Andrea Dawn Foebel, Ralf Kuja-Halkola, Ida Karlsson, Nancy Lee Pedersen, Sara Hägg, Juulia Jylhävä,

https://doi.org/10.18632/aging.101352 pp 2629—2646

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Clock mediates liver senescence by controlling ER stress

Gongsheng Yuan, Bingxuan Hua, Tingting Cai, Lirong Xu, Ermin Li, Yiqing Huang, Ning Sun, Zuoqin Yan, Chao Lu, Ruizhe Qian,

https://doi.org/10.18632/aging.101353 pp 2647—2665

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Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression

Rahul Bhome, Rebecca W. Goh, Marc D. Bullock, Nir Pillar, Stephen M. Thirdborough, Massimiliano Mellone, Reza Mirnezami, Dieter Galea, Kirill Veselkov, Quan Gu, Timothy J. Underwood, John N. Primrose, Olivier De Wever, Noam Shomron, A. Emre Sayan, Alex H. Mirnezami,

https://doi.org/10.18632/aging.101355 pp 2666—2694

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A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas

Djihad Hadjadj, Su-Jung Kim, Thomas Denecker, Laura Ben Driss, Jean-Charles Cadoret, Chrystelle Maric, Giuseppe Baldacci, Fabien Fauchereau,

https://doi.org/10.18632/aging.101356 pp 2695—2716

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