Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 10, Issue 10

October 2018
pp 2535—3041

About the Cover

The cover for issue 10 of Aging features Figure 1 "Quantitative description of human locomotor activity tracks" from Pyrkov et al.

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Editorials

Early-life stress and life

Yusuke Takatsuru,

https://doi.org/10.18632/aging.101568 pp 2535—2536

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Alzheimer's Disease, time to turn the tide

Stefano L. Sensi,

https://doi.org/10.18632/aging.101581 pp 2537—2538

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Brain precursor cells' failure in neurodegeneration

Tamir Ben-Hur, Nina Fainstein,

https://doi.org/10.18632/aging.101593 pp 2539—2540

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Memory and menopause: an unsolved puzzle

Adrian Angenendt, Romy Steiner, Arne Knörck, Gertrud Schwär, Maik Konrad, Elmar Krause, Annette Lis,

https://doi.org/10.18632/aging.101596 pp 2541—2543

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Mutant ubiquitin reduces Aβ plaques

Bert M. Verheijen, Fred W. van Leeuwen,

https://doi.org/10.18632/aging.101598 pp 2544—2546

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Frontotemporal dementia: a neurophysiological study

Flavio Di Stasio, Antonio Suppa, Alfredo Berardelli,

https://doi.org/10.18632/aging.101604 pp 2547—2548

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Identifying ubiquitinated proteins and aggregates

Nathan Basisty, Birgit Schilling, Peter S. Rabinovitch,

https://doi.org/10.18632/aging.101605 pp 2549—2550

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Age-related changes in 'hub' neurons

Abbi R. Hernandez, Sara N. Burke,

https://doi.org/10.18632/aging.101606 pp 2551—2552

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Why do on-pump patients live longer?

Nicola King, Val Mann,

https://doi.org/10.18632/aging.101607 pp 2553—2554

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Accelerated atherosclerosis in HGPS

Magda R. Hamczyk, Vicente Andrés,

https://doi.org/10.18632/aging.101608 pp 2555—2556

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Theory Article

Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis

Samuil Umansky,

https://doi.org/10.18632/aging/101612 pp 2557—2569

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Research Papers

CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling

Zhao Liu, Mi Chen, Lin-Ka Xie, Ting Liu, Zhen-Wei Zou, Yong Li, Peng Chen, Xin Peng, Charlie Ma, Wen-Jie Zhang, Pin-Dong Li,

https://doi.org/10.18632/aging.101571 pp 2570—2584

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H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions

Alena Svobodová Kovaříková, Soňa Legartová, Jana Krejčí, Eva Bártová,

https://doi.org/10.18632/aging.101572 pp 2585—2605

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Circular RNA circUBXN7 represses cell growth and invasion by sponging miR-1247-3p to enhance B4GALT3 expression in bladder cancer

Hongwei Liu, Dongliang Chen, Junming Bi, Jinli Han, Meihua Yang, Wei Dong, Tianxin Lin, Jian Huang,

https://doi.org/10.18632/aging.101573 pp 2606—2623

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A joint analysis of metabolomic profiles associated with muscle mass and strength in Caucasian women

Qi Zhao, Hui Shen, Kuan-Jui Su, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Timothy J. Garrett, Jiawang Liu, David Kakhniashvili, Hong-Wen Deng,

https://doi.org/10.18632/aging.101574 pp 2624—2635

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Inflammation markers are associated with frailty in elderly patients with coronary heart disease

Ping Hou, Hui-Ping Xue, Xin-E Mao, Yong-Nan Li, Lin-Feng Wu, Yong-Bing Liu,

https://doi.org/10.18632/aging.101575 pp 2636—2645

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The fasting blood glucose and long non-coding RNA SNHG8 predict poor prognosis in patients with gastric carcinoma after radical gastrectomy

Yunchai Lin, Dan Hu, Qiang Zhou, Xiangdong Lin, Jinxiu Lin, Feng Peng,

https://doi.org/10.18632/aging.101576 pp 2646—2656

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A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of C. elegans

Berenice Franco-Juárez, Fanny Mejía-Martínez, Elizabeth Moreno-Arriola, Alain Hernández-Vázquez, Saul Gómez-Manzo, Jaime Marcial-Quino, Roberto Arreguín-Espinosa, Antonio Velázquez-Arellano, Daniel Ortega-Cuellar,

https://doi.org/10.18632/aging.101577 pp 2657—2667

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High expression of the breast cancer susceptibility gene BRCA1 in long-lived termite kings

Eisuke Tasaki, Yuki Mitaka, Tomonari Nozaki, Kazuya Kobayashi, Kenji Matsuura, Yoshihito Iuchi,

https://doi.org/10.18632/aging.101578 pp 2668—2683

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Searching for longevity hotspots in Denmark

Anne Vinkel Hansen, Laust Hvas Mortensen, Rudi Westendorp,

https://doi.org/10.18632/aging.101579 pp 2684—2694

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Role of alternative splicing of VEGF-A in the development of atherosclerosis

Naishi Zhao, Jianfeng Zhang,

https://doi.org/10.18632/aging.101580 pp 2695—2708

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Increased environmental temperature normalizes energy metabolism outputs between normal and Ames dwarf mice

Justin Darcy, Samuel McFadden, Yimin Fang, Darlene E. Berryman, Edward O. List, Nicholas Milcik, Andrzej Bartke,

https://doi.org/10.18632/aging.101582 pp 2709—2722

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Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

Yuji Morita, Kenta Jounai, Akihiko Sakamoto, Yasuyuki Tomita, Yoshihiko Sugihara, Hiroaki Suzuki, Konomi Ohshio, Masato Otake, Daisuke Fujiwara, Osamu Kanauchi, Mitsuo Maruyama,

https://doi.org/10.18632/aging.101583 pp 2723—2740

View Abstract PDF Full-Text How to Cite Special Collection on Eye Disease

A single-nucleotide polymorphism (rs1805087) in the methionine synthase (METH) gene increases the risk of prostate cancer

Xiaosong Zhang, Jilei Tang, Nan Shen, Kewei Ren,

https://doi.org/10.18632/aging.101584 pp 2741—2754

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Pretreatment TACC3 expression in locally advanced rectal cancer decreases the response to neoadjuvant chemoradiotherapy

Wen-juan Ma, Yang-kui Gu, Jian-hong Peng, Xue-cen Wang, Xin Yue, Zhi-zhong Pan, Gong Chen, Hai-neng Xu, Zhong-guo Zhou, Rong-xin Zhang,

https://doi.org/10.18632/aging.101585 pp 2755—2771

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Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy

Beiyun Wang, Yuan Zhong, Qinjie Li, Liang Cui, Gaozhong Huang,

https://doi.org/10.18632/aging.101586 pp 2772—2782

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Ubiquitin-speciﬁc protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition

Chan Qiu, Yan Liu, Ying Mei, Min Zou, Zhibo Zhao, Mingxin Ye, Xiaoling Wu,

https://doi.org/10.18632/aging.101587 pp 2783—2799

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Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression

Sylwia Kabacik, Steve Horvath, Howard Cohen, Kenneth Raj,

https://doi.org/10.18632/aging.101588 pp 2800—2815

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies

Mulin Xu, Yu Liu, Yi Huang, Jinli Wang, Jinhua Yan, Le Zhang, Cuntai Zhang,

https://doi.org/10.18632/aging.101589 pp 2816—2831

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A multi-tissue full lifespan epigenetic clock for mice

Michael J. Thompson, Karolina Chwiałkowska, Liudmilla Rubbi, Aldons J. Lusis, Richard C. Davis, Anuj Srivastava, Ron Korstanje, Gary A. Churchill, Steve Horvath, Matteo Pellegrini,

https://doi.org/10.18632/aging.101590 pp 2832—2854

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells

Angelica Giuliani, Ilenia Cirilli, Francesco Prattichizzo, Emanuela Mensà, Gianluca Fulgenzi, Jacopo Sabbatinelli, Laura Graciotti, Fabiola Olivieri, Antonio Domenico Procopio, Luca Tiano, Maria Rita Rippo,

https://doi.org/10.18632/aging.101591 pp 2855—2873

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Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism

Junxiang Yin, Shiping Li, Megan Nielsen, Tanner Carcione, Winnie S. Liang, Jiong Shi,

https://doi.org/10.18632/aging.101592 pp 2874—2883

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Radiogenomics of lower-grade gliomas: a radiomic signature as a biological surrogate for survival prediction

Zenghui Qian, Yiming Li, Zhiyan Sun, Xing Fan, Kaibin Xu, Kai Wang, Shaowu Li, Zhong Zhang, Tao Jiang, Xing Liu, Yinyan Wang,

https://doi.org/10.18632/aging.101594 pp 2884—2899

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Can mesenchymal stem cell lysate reverse aging?

Ming-Fen Hsu, Szu-Hsien Yu, Sheng-Ju Chuang, Tom Kwang-Chun Kuo, Pawan K. Singal, Chih-Yang Huang, Chung-Lan Kao, Chia-Hua Kuo,

https://doi.org/10.18632/aging.101595 pp 2900—2910

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Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging

Francesca Casciaro, Francesca Beretti, Manuela Zavatti, James A. McCubrey, Stefano Ratti, Sandra Marmiroli, Matilde Y. Follo, Tullia Maraldi,

https://doi.org/10.18632/aging.101599 pp 2911—2934

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The influence of the TNFα rs1800629 polymorphism on some inflammatory biomarkers in 45-60-year-old women with metabolic syndrome

Małgorzata Szkup, Elżbieta Chełmecka, Anna Lubkowska, Aleksander Jerzy Owczarek, Elżbieta Grochans,

https://doi.org/10.18632/aging.101600 pp 2935—2943

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XRCC1 gene polymorphisms and risk of neuroblastoma in Chinese children

Jiao Zhang, Zhenjian Zhuo, Wenya Li, Jinhong Zhu, Jing He, Jinsong Su,

https://doi.org/10.18632/aging.101601 pp 2944—2953

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Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress

Jia Fang, Yuan Yan, Xin Teng, Xinyu Wen, Na Li, Sha Peng, Wenshuai Liu, F. Xavier Donadeu, Shanting Zhao, Jinlian Hua,

https://doi.org/10.18632/aging.101602 pp 2954—2972

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Quantitative characterization of biological age and frailty based on locomotor activity records

Timothy V. Pyrkov, Evgeny Getmantsev, Boris Zhurov, Konstantin Avchaciov, Mikhail Pyatnitskiy, Leonid Menshikov, Kristina Khodova, Andrei V. Gudkov, Peter O. Fedichev,

https://doi.org/10.18632/aging.101603 pp 2973—2990

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Sirt1/Nrf2 pathway is involved in oocyte aging by regulating Cyclin B1

Rujun Ma, Wei Liang, Qin Sun, Xuhua Qiu, Ying Lin, Xie Ge, Kadiliya Jueraitetibaike, Min Xie, Ji Zhou, Xuan Huang, Qiang Wang, Li Chen, Bing Yao,

https://doi.org/10.18632/aging.101609 pp 2991—3004

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Longitudinal changes in leukocyte telomere length and mortality in elderly Swedish men

Xiaotian Yuan, Magnus Kronström, Mai-Lis Hellenius, Tommy Cederholm, Dawei Xu, Per Sjögren,

https://doi.org/10.18632/aging.101611 pp 3005—3016

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Age- and sex-dependent changes in levels of circulating brain-enriched microRNAs during normal aging

Kira Sheinerman, Vladimir Tsivinsky, Aabhas Mathur, Debra Kessler, Beth Shaz, Samuil Umansky,

https://doi.org/10.18632/aging.101613 pp 3017—3041

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