Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 11, Issue 10

31 May, 2019
pp 2912—3409

About the Cover

The cover features Figure 4 "Experiment scheme and confirmation of virus transduction in the brain" from Whittemore et al.

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Editorials

White matter hyperintensities and neurodegenerative dementias

Celeste Sassi,

https://doi.org/10.18632/aging.101967 pp 2912—2913

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The changing landscape of interventional cardiology

Richard J. Jabbour, Azeem Latib,

https://doi.org/10.18632/aging.102005 pp 2914—2915

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Priority Research Paper

Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice

Kurt Whittemore, Aksinya Derevyanko, Paula Martinez, Rosa Serrano, Martí Pumarola, Fàtima Bosch, Maria A. Blasco,

https://doi.org/10.18632/aging.101982 pp 2916—2948

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Research Papers

Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline

Yasuhisa Ano, Yuka Yoshino, Toshiko Kutsukake, Rena Ohya, Takafumi Fukuda, Kazuyuki Uchida, Akihiko Takashima, Hiroyuki Nakayama,

https://doi.org/10.18632/aging.101909 pp 2949—2967

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The small non-coding RNA profile of mouse oocytes is modified during aging

Bettina P. Mihalas, Nicole J. Camlin, Miguel J. Xavier, Alexandra E. Peters, Janet E. Holt, Jessie M. Sutherland, Eileen A. McLaughlin, Andrew L. Eamens, Brett Nixon,

https://doi.org/10.18632/aging.101947 pp 2968—2997

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Beneficial effects of Cripto-1 for transarterial chemoembolization in hepatocellular carcinoma

Xiao-shan Li, Jia-hong Wang, Xian-zi Yang, Lei Ma, Yan-xia Shi, Ye Song, Peng Jiang, Sha Gao, Ye Dong, Jin-rong Lin, Chuan Jin,

https://doi.org/10.18632/aging.101951 pp 2998—3011

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Epigenetic clock analysis of human fibroblasts in vitro: effects of hypoxia, donor age, and expression of hTERT and SV40 largeT

Mieko Matsuyama, David J. WuWong, Steve Horvath, Shigemi Matsuyama,

https://doi.org/10.18632/aging.101955 pp 3012—3022

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

Measuring successful aging: an exploratory factor analysis of the InCHIANTI Study into different health domains

Sarah Mount, Luigi Ferrucci, Anke Wesselius, Maurice P. Zeegers, Annemie MWJ Schols,

https://doi.org/10.18632/aging.101957 pp 3023—3040

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LncRNA HMMR-AS1 promotes proliferation and metastasis of lung adenocarcinoma by regulating MiR-138/sirt6 axis

Yong Cai, Zhaoying Sheng, Yun Chen, Jiying Wang,

https://doi.org/10.18632/aging.101958 pp 3041—3054

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MiR-320a induces diabetic nephropathy via inhibiting MafB

Mengying He, Jin Wang, Zhongwei Yin, Yanru Zhao, Huiying Hou, Jiahui Fan, Huaping Li, Zheng Wen, Jiarong Tang, Yan Wang, Dao Wen Wang, Chen Chen,

https://doi.org/10.18632/aging.101962 pp 3055—3079

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The in vitro effects of gibberellin on human sperm motility

Chun-Shuang Xu, Yi Zhou, Zhou Jiang, Li-E Wang, Jiao-Jiao Huang, Tian-Yu Zhang, Yong Zhao, Wei Shen, Shu-Hua Zou, Li-Li Zang,

https://doi.org/10.18632/aging.101963 pp 3080—3093

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Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells

Ge Zhou, Rong-kui Hu, Gui-cheng Xia, Shi-hai Yan, Qing-ling Ren, Juan Zhao, Fei-hong Wang, Cheng-cai Huang, Qi Yao, Yong Tan, Ning-wei Zhao,

https://doi.org/10.18632/aging.101964 pp 3094—3116

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Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong Xu, Xu Zhang,

https://doi.org/10.18632/aging.101966 pp 3117—3137

View Abstract PDF Full-Text How to Cite Special Collection on Eye Disease

Comparison between physical and cognitive treatment in patients with MCI and Alzheimer’s disease

Cristina Fonte, Nicola Smania, Anna Pedrinolla, Daniele Munari, Marialuisa Gandolfi, Alessandro Picelli, Valentina Varalta, Maria V. Benetti, Annalisa Brugnera, Angela Federico, Ettore Muti, Stefano Tamburin, Federico Schena, Massimo Venturelli,

https://doi.org/10.18632/aging.101970 pp 3138—3155

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Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study

Wei Xu, Can Zhang, Jie-Qiong Li, Chen-Chen Tan, Xi-Peng Cao, Lan Tan, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative,

https://doi.org/10.18632/aging.101971 pp 3156—3169

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DNA hydroxymethylation combined with carotid plaques as a novel biomarker for coronary atherosclerosis

Dan Jiang, Ying Wang, Guanglei Chang, Qin Duan, Linna You, Min Sun, Chunxiao Hu, Lei Gao, Shiyong Wu, Hongmei Tao, Kai Lu, Dongying Zhang,

https://doi.org/10.18632/aging.101972 pp 3170—3181

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Aberration methylation of miR-34b was involved in regulating vascular calcification by targeting Notch1

Xiao Lin, Fuxingzi Li, Feng Xu, Rong-Rong Cui, Dan Xiong, Jia-Yu Zhong, Ting Zhu, Su-Kang Shan, Feng Wu, Xu-Biao Xie, Xiao-Bo Liao, Ling-Qing Yuan,

https://doi.org/10.18632/aging.101973 pp 3182—3197

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Simvastatin induces breast cancer cell death through oxidative stress up-regulating miR-140-5p

Fuliang Bai, Ze Yu, Xin Gao, Jiawei Gong, Lizhi Fan, Feifei Liu,

https://doi.org/10.18632/aging.101974 pp 3198—3219

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Association of RAGE gene multiple variants with the risk for COPD and asthma in northern Han Chinese

Hongtao Niu, Wenquan Niu, Tao Yu, Feng Dong, Ke Huang, Ruirui Duan, Shiwei Qumu, Minya Lu, Yong Li, Ting Yang, Chen Wang,

https://doi.org/10.18632/aging.101975 pp 3220—3237

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Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation

Steve Horvath, Ake T. Lu, Howard Cohen, Ken Raj,

https://doi.org/10.18632/aging.101976 pp 3238—3249

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

A small molecular inhibitor of LRRK1 identified by homology modeling and virtual screening suppresses osteoclast function, but not osteoclast differentiation, in vitro

Mingjue Si, Canjun Zeng, Helen Goodluck, Sandi Shen, Subburaman Mohan, Weirong Xing,

https://doi.org/10.18632/aging.101977 pp 3250—3261

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Abnormal gut microbiota composition contributes to cognitive dysfunction in streptozotocin-induced diabetic mice

Fan Yu, Wei Han, Gaofeng Zhan, Shan Li, Shoukui Xiang, Bin Zhu, Xiaohong Jiang, Ling Yang, Ailin Luo, Fei Hua, Chun Yang,

https://doi.org/10.18632/aging.101978 pp 3262—3279

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Brain-specific NRSF deficiency aggravates dopaminergic neurodegeneration and impairs neurogenesis in the MPTP mouse model of Parkinson’s disease

Dongping Huang, Qing Li, Yi Wang, Zhaolin Liu, Zishan Wang, Heng Li, Jinghui Wang, Jing Su, Yuanyuan Ma, Mei Yu, Jian Fei, Fang Huang,

https://doi.org/10.18632/aging.101979 pp 3280—3297

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GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple‐negative breast cancer via upregulation of Smad7

Tian Zhou, Lei Yu, Jianjun Huang, Xueke Zhao, Yanwen Li, Yaxin Hu, Yu Lei,

https://doi.org/10.18632/aging.101983 pp 3298—3314

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Effect of chronic nitrate and citrulline supplementation on vascular function and exercise performance in older individuals

Thibault Le Roux-Mallouf, Felix Pelen, Angela Vallejo, Idir Halimaoui, Stéphane Doutreleau, Samuel Verges,

https://doi.org/10.18632/aging.101984 pp 3315—3332

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Prediction of competing endogenous RNA coexpression network as prognostic markers in AML

Jun-Dan Wang, Hong-Sheng Zhou, Xi-Xiang Tu, Yi He, Qi-Fa Liu, Quentin Liu, Zi-Jie Long,

https://doi.org/10.18632/aging.101985 pp 3333—3347

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circFADS2 protects LPS-treated chondrocytes from apoptosis acting as an interceptor of miR-498/mTOR cross-talking

Guoqing Li, Wei Tan, Yuxuan Fang, Xia Wu, Wei Zhou, Chunwang Zhang, Yu Zhang, Yanqing Liu, Guangzheng Jiu, Dan Liu,

https://doi.org/10.18632/aging.101986 pp 3348—3361

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Circular RNA hsa_circ_0001649 inhibits hepatocellular carcinoma progression via multiple miRNAs sponge

Yang Su, Chao Xu, Yuting Liu, Yilin Hu, Haiyan Wu,

https://doi.org/10.18632/aging.101988 pp 3362—3375

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MicroRNA-335/ID4 dysregulation predicts clinical outcome and facilitates leukemogenesis by activating PI3K/Akt signaling pathway in acute myeloid leukemia

Jing-dong Zhou, Xi-xi Li, Ting-juan Zhang, Zi-jun Xu, Zhi-hui Zhang, Yu Gu, Xiang-mei Wen, Wei Zhang, Run-bi Ji, Zhao-qun Deng, Jiang Lin, Jun Qian,

https://doi.org/10.18632/aging.101991 pp 3376—3391

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Review

Independent ischemic stroke risk factors in older Americans: a systematic review

Jonathan Singer, Deborah Gustafson, Caroline Cummings, Aron Egelko, Jack Mlabasati, Alyssa Conigliaro, Steven R. Levine,

https://doi.org/10.18632/aging.101987 pp 3392—3407

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Correction

Correction for: Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition

Chan Qiu, Yan Liu, Ying Mei, Min Zou, Zhibo Zhao, Mingxin Ye, Xiaoling Wu,

https://doi.org/10.18632/aging.102010 pp 3408—3409

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Featured Nobel Articles

Volume 11, Issue 10

About the Cover

Editorials

Celeste Sassi,

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Richard J. Jabbour, Azeem Latib,

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Kurt Whittemore, Aksinya Derevyanko, Paula Martinez, Rosa Serrano, Martí Pumarola, Fàtima Bosch, Maria A. Blasco,

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Research Papers

Yasuhisa Ano, Yuka Yoshino, Toshiko Kutsukake, Rena Ohya, Takafumi Fukuda, Kazuyuki Uchida, Akihiko Takashima, Hiroyuki Nakayama,

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Bettina P. Mihalas, Nicole J. Camlin, Miguel J. Xavier, Alexandra E. Peters, Janet E. Holt, Jessie M. Sutherland, Eileen A. McLaughlin, Andrew L. Eamens, Brett Nixon,

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Xiao-shan Li, Jia-hong Wang, Xian-zi Yang, Lei Ma, Yan-xia Shi, Ye Song, Peng Jiang, Sha Gao, Ye Dong, Jin-rong Lin, Chuan Jin,

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Mieko Matsuyama, David J. WuWong, Steve Horvath, Shigemi Matsuyama,

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Sarah Mount, Luigi Ferrucci, Anke Wesselius, Maurice P. Zeegers, Annemie MWJ Schols,

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Yong Cai, Zhaoying Sheng, Yun Chen, Jiying Wang,

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Mengying He, Jin Wang, Zhongwei Yin, Yanru Zhao, Huiying Hou, Jiahui Fan, Huaping Li, Zheng Wen, Jiarong Tang, Yan Wang, Dao Wen Wang, Chen Chen,

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Chun-Shuang Xu, Yi Zhou, Zhou Jiang, Li-E Wang, Jiao-Jiao Huang, Tian-Yu Zhang, Yong Zhao, Wei Shen, Shu-Hua Zou, Li-Li Zang,

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Ge Zhou, Rong-kui Hu, Gui-cheng Xia, Shi-hai Yan, Qing-ling Ren, Juan Zhao, Fei-hong Wang, Cheng-cai Huang, Qi Yao, Yong Tan, Ning-wei Zhao,

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Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong Xu, Xu Zhang,

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Cristina Fonte, Nicola Smania, Anna Pedrinolla, Daniele Munari, Marialuisa Gandolfi, Alessandro Picelli, Valentina Varalta, Maria V. Benetti, Annalisa Brugnera, Angela Federico, Ettore Muti, Stefano Tamburin, Federico Schena, Massimo Venturelli,

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Wei Xu, Can Zhang, Jie-Qiong Li, Chen-Chen Tan, Xi-Peng Cao, Lan Tan, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative,

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Dan Jiang, Ying Wang, Guanglei Chang, Qin Duan, Linna You, Min Sun, Chunxiao Hu, Lei Gao, Shiyong Wu, Hongmei Tao, Kai Lu, Dongying Zhang,

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Xiao Lin, Fuxingzi Li, Feng Xu, Rong-Rong Cui, Dan Xiong, Jia-Yu Zhong, Ting Zhu, Su-Kang Shan, Feng Wu, Xu-Biao Xie, Xiao-Bo Liao, Ling-Qing Yuan,

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Fuliang Bai, Ze Yu, Xin Gao, Jiawei Gong, Lizhi Fan, Feifei Liu,

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Hongtao Niu, Wenquan Niu, Tao Yu, Feng Dong, Ke Huang, Ruirui Duan, Shiwei Qumu, Minya Lu, Yong Li, Ting Yang, Chen Wang,

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