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The cover features Figure 3 "Frailty-associated biological pathways in blacks." from Prince et al.

Volume 11, Issue 15

15 August, 2019
pp 5287—5863

About the Cover

The cover features Figure 3 "Frailty-associated biological pathways in blacks." from Prince et al.


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Editorials

Physical exercise, autophagy and cardiometabolic stress in aging

Haili Tian, Peijie Chen, Jun Ren,
https://doi.org/10.18632/aging.102129 pp 5287—5288
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Nrf2, stress and aging

Ioannis P. Trougakos,
https://doi.org/10.18632/aging.102143 pp 5289—5291
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Closed-loop management of inpatient hyperglycemia

Charlotte K. Boughton, Lia Bally, Roman Hovorka,
https://doi.org/10.18632/aging.102144 pp 5292—5293
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MicroRNA dysregulation influences growth hormone signaling

Amy E. Elias, Jill A. Kreiling,
https://doi.org/10.18632/aging.102145 pp 5294—5295
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Glucose dysregulation in pre-clinical Alzheimer’s disease

Niamh M. C. Connolly, Pierre Theurey, Paola Pizzo,
https://doi.org/10.18632/aging.102146 pp 5296—5297
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The risk of jiggly fat in aging

Patricia Corrales, Marina Martín-Taboada, Gema Medina-Gomez,
https://doi.org/10.18632/aging.102147 pp 5298—5299
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Research Papers

Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2

Lei Yu, Si Gui, Yawei Liu, Xiaoyu Qiu, Guozhong Zhang, Xi’an Zhang, Jun Pan, Jun Fan, Songtao Qi, Binghui Qiu,
https://doi.org/10.18632/aging.102092 pp 5300—5318
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Association of basal metabolic rate and fuel oxidation in basal conditions and during exercise, with plasma S-klotho: the FIT-AGEING study

Francisco J. Amaro-Gahete, Alejandro De-la-O, Lucas Jurado-Fasoli, Jonatan R. Ruiz, Manuel J. Castillo,
https://doi.org/10.18632/aging.102100 pp 5319—5333
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Down-regulation of long non-coding RNA MEG3 suppresses osteogenic differentiation of periodontal ligament stem cells (PDLSCs) through miR-27a-3p/IGF1 axis in periodontitis

Yi Liu, Chunpeng Liu, Ankui Zhang, Shichang Yin, Ting Wang, Yan Wang, Meiming Wang, Yixin Liu, Qiaohui Ying, Jinrui Sun, Fulan Wei, Dongxu Liu, Chunling Wang, Shaohua Ge,
https://doi.org/10.18632/aging.102105 pp 5334—5350
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Long intergenic non-protein coding RNA 511 promotes the progression of osteosarcoma cells through sponging microRNA 618 to upregulate the expression of maelstrom

Wen Guo, Qing Yu, Ming Zhang, Fang Li, Yu Liu, Weiwei Jiang, Haitao Jiang, Haijun Li,
https://doi.org/10.18632/aging.102109 pp 5351—5367
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Downregulation of microRNA-218 is cardioprotective against cardiac fibrosis and cardiac function impairment in myocardial infarction by binding to MITF

Linfeng Qian, Shaobo Pan, Liping Shi, Yongyi Zhou, Lai Sun, Zhedong Wan, Yufang Ding, Jia Qian,
https://doi.org/10.18632/aging.102112 pp 5368—5388
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Abnormalities of saccadic eye movements in dementia due to Alzheimer’s disease and mild cognitive impairment

Thomas D.W. Wilcockson, Diako Mardanbegi, Baiqiang Xia, Simon Taylor, Pete Sawyer, Hans W. Gellersen, Ira Leroi, Rebecca Killick, Trevor J. Crawford,
https://doi.org/10.18632/aging.102118 pp 5389—5398
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Age-related changes in human sperm DNA integrity

Aleksandra Rosiak-Gill, Kamil Gill, Joanna Jakubik, Monika Fraczek, Lukasz Patorski, Dariusz Gaczarzewicz, Rafał Kurzawa, Maciej Kurpisz, Malgorzata Piasecka,
https://doi.org/10.18632/aging.102120 pp 5399—5411
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Sex differences in the associations of placental epigenetic aging with fetal growth

Fasil Tekola-Ayele, Tsegaselassie Workalemahu, Gezahegn Gorfu, Deepika Shrestha, Benjamin Tycko, Ronald Wapner, Cuilin Zhang, Germaine M. Buck Louis,
https://doi.org/10.18632/aging.102124 pp 5412—5432
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Genome-wide association study identifies CBFA2T3 affecting the rate of CSF Aβ42 decline in non-demented elders

Kai-Xin Dou, Can Zhang, Chen-Chen Tan, Wei Xu, Jie-Qiong Li, Xi-Peng Cao, Lan Tan, Jin-Tai Yu, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI),
https://doi.org/10.18632/aging.102125 pp 5433—5444
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Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells

Laura A. Henze, Trang T.D. Luong, Beate Boehme, Jaber Masyout, Markus P. Schneider, Sebastian Brachs, Florian Lang, Burkert Pieske, Andreas Pasch, Kai-Uwe Eckardt, Jakob Voelkl, Ioana Alesutan,
https://doi.org/10.18632/aging.102130 pp 5445—5462
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Large-scale analysis reveals the specific clinical and immune features of CD155 in glioma

Fangkun Liu, Jing Huang, Yuanyuan Xiong, Shuwang Li, Zhixiong Liu,
https://doi.org/10.18632/aging.102131 pp 5463—5482
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CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma

Xiaoping Zhong, Anna Kan, Wancong Zhang, Jianda Zhou, Huayong Zhang, Jiasheng Chen, Shijie Tang,
https://doi.org/10.18632/aging.102132 pp 5483—5497
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Environmental exposure to polybrominated biphenyl (PBB) associates with an increased rate of biological aging

Sarah W. Curtis, Dawayland O. Cobb, Varun Kilaru, Metrecia L. Terrell, M. Elizabeth Marder, Dana Boyd Barr, Carmen J. Marsit, Michele Marcus, Karen N. Conneely, Alicia K. Smith,
https://doi.org/10.18632/aging.102134 pp 5498—5517
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Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome

Calais S. Prince, Nicole Noren Hooten, Nicolle A. Mode, Yongqing Zhang, Ngozi Ejiogu, Kevin G. Becker, Alan B. Zonderman, Michele K. Evans,
https://doi.org/10.18632/aging.102135 pp 5518—5534
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HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress

Yiru Wang, Caixia Yang, Nahla Abdalla Hassan Elsheikh, Chengmin Li, Fangxiao Yang, Genlin Wang, Lian Li,
https://doi.org/10.18632/aging.102136 pp 5535—5547
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Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury

Sun Woo Lim, Yoo Jin Shin, Kang Luo, Yi Quan, Sheng Cui, Eun Jeong Ko, Byung Ha Chung, Chul Woo Yang,
https://doi.org/10.18632/aging.102137 pp 5548—5569
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Effects of inflammatory responses, apoptosis, and STAT3/NF-κB- and Nrf2-mediated oxidative stress on benign prostatic hyperplasia induced by a high-fat diet

Yongzhi Li, Benkang Shi, Fengming Dong, Xingwang Zhu, Bing Liu, Yili Liu,
https://doi.org/10.18632/aging.102138 pp 5570—5578
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Integrative analysis of DNA methylation and gene expression to identify key epigenetic genes in glioblastoma

Danyun Jia, Wei Lin, Hongli Tang, Yifan Cheng, Kaiwei Xu, Yanshu He, Wujun Geng, Qinxue Dai,
https://doi.org/10.18632/aging.102139 pp 5579—5592
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TGFβ1- miR-140-5p axis mediated up-regulation of Flap Endonuclease 1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

Chuanfei Li, Di Zhou, Hao Hong, Shuangyan Yang, Li Zhang, Shiying Li, Peng Hu, Hong Ren, Zhechuan Mei, Hui Tang,
https://doi.org/10.18632/aging.102140 pp 5593—5612
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Androgen deprivation therapy increases brain ageing

Julio Plata-Bello, Ana Plata-Bello, Yaiza Pérez-Martín, Victor Fajardo, Tomás Concepción-Massip,
https://doi.org/10.18632/aging.102142 pp 5613—5627
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Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age

Melod Mehdipour, Jessy Etienne, Chia-Chien Chen, Ranveer Gathwala, Maryam Rehman, Cameron Kato, Chao Liu, Yutong Liu, Yi Zuo, Michael J. Conboy, Irina M. Conboy,
https://doi.org/10.18632/aging.102148 pp 5628—5645
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The long noncoding RNA MIR210HG promotes tumor metastasis by acting as a ceRNA of miR-1226-3p to regulate mucin-1c expression in invasive breast cancer

Xiao-yu Li, Li-ye Zhou, Hao Luo, Qi Zhu, Liang Zuo, Gu-yue Liu, Chu Feng, Jun-yong Zhao, Yuan-yuan Zhang, Xue Li,
https://doi.org/10.18632/aging.102149 pp 5646—5665
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Overexpressed pseudogenes, DUXAP8 and DUXAP9, promote growth of renal cell carcinoma and serve as unfavorable prognostic biomarkers

Jing Chen, Weiyang Lou, Bisha Ding, Xian Wang,
https://doi.org/10.18632/aging.102152 pp 5666—5688
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Up-regulation of SPC25 promotes breast cancer

Qian Wang, Yanhui Zhu, Zhouxiao Li, Qian Bu, Tong Sun, Hanjin Wang, Handong Sun, Xiufeng Cao,
https://doi.org/10.18632/aging.102153 pp 5689—5704
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LncRNA ADAMTS9-AS2 inhibits cell proliferation and decreases chemoresistance in clear cell renal cell carcinoma via the miR-27a-3p/FOXO1 axis

Er-lin Song, Li Xing, Liang Wang, Wen-ting Song, Dan-bin Li, Yi Wang, Yi-wei Gu, Ming-ming Liu, Wen-jun Ni, Peng Zhang, Xin Ma, Xu Zhang, Jie Yao, Yang Chen, Rui-hua An,
https://doi.org/10.18632/aging.102154 pp 5705—5725
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Conserved roles of glucose in suppressing reactive oxygen species-induced cell death and animal survival

Congrong Wang, Yinan Zhang, Fengwen Li, Yuehua Wei,
https://doi.org/10.18632/aging.102155 pp 5726—5743
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miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN

Ming He, Peng Shen, Chuang Qiu, Jiashi Wang,
https://doi.org/10.18632/aging.102157 pp 5744—5756
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Identification and characterization of telocytes in rat testis

Yifei Liu, Yu Liang, Siyi Wang, Imran Tarique, Waseem Ali Vistro, Haiyan Zhang, Abdul Haseeb, Noor Samad Gandahi, Adeela Iqbal, Tianci An, Huan Yang, Qiusheng Chen, Ping Yang,
https://doi.org/10.18632/aging.102158 pp 5757—5768
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The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells

Jialiang Wang, Huan Wei, Yanlin Huang, Dongmei Chen, Guofen Zeng, Yifan Lian, Yuehua Huang,
https://doi.org/10.18632/aging.102165 pp 5769—5785
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A defined human aging phenome

Søren Norge Andreassen, Michael Ben Ezra, Morten Scheibye-Knudsen,
https://doi.org/10.18632/aging.102166 pp 5786—5806
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Association between healthy vascular aging and the risk of the first stroke in a community-based Chinese cohort

Yingying Yang, Anxin Wang, Xiaodong Yuan, Quanhui Zhao, Xiaoxue Liu, Shuohua Chen, Xiuyan Wang, Yongjun Wang, Shouling Wu, Yilong Wang,
https://doi.org/10.18632/aging.102170 pp 5807—5816
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The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

Nicola Alessio, Domenico Aprile, Tiziana Squillaro, Giovanni Di Bernardo, Mauro Finicelli, Mariarosa AB Melone, Gianfranco Peluso, Umberto Galderisi,
https://doi.org/10.18632/aging.102172 pp 5817—5828
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Long non-coding RNA CASC19 is associated with the progression and prognosis of advanced gastric cancer

Wen-Jie Wang, Chang-An Guo, Rui Li, Zi-Peng Xu, Jian-Ping Yu, Yan Ye, Jun Zhao, Jing Wang, Wen-An Wang, An Zhang, Hong-Tao Li, Chen Wang, Hong-Bin Liu,
https://doi.org/10.18632/aging.102190 pp 5829—5847
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Sodium cantharidate targets STAT3 and abrogates EGFR inhibitor resistance in osteosarcoma

Xiang Lu Ji, Ming He,
https://doi.org/10.18632/aging.102193 pp 5848—5863
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