Online ISSN: 1945-4589
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Aging-US Volume 3, Issue 3 Cover

Volume 3, Issue 3

March 2011
pp 179—328
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Commentaries

Eating less suppresses microRNA assassins in the brain

Emmette Hutchison, Mark P. Mattson,
https://doi.org/10.18632/aging.100287 pp 179—180
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Spontaneous inactivating p53 mutations and the “selfish cell”

Steven M. Sorscher, Aubrey E. Hill, Roger Belizaire, Eric J. Sorscher,
https://doi.org/10.18632/aging.100294 pp 181
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MicroRNA - a contributor to age-associated neural stem cell dysfunction?

Muhammad Amir Khan, Dieter Chichung Lie,
https://doi.org/10.18632/aging.100297 pp 182—183
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Phylogenetic ubiquity of the effects of altered ubiquinone biosynthesis on survival

Siegfried Hekimi, Bryan Hughes,
https://doi.org/10.18632/aging.100310 pp 184—185
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Commentaries and Editorials

The Smc5/6 complex and the difficulties cutting the ties of twin sisters

Jean-François Noël, Raymund J. Wellinger,
https://doi.org/10.18632/aging.100295 pp 186—188
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Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex

Philippe Major,
https://doi.org/10.18632/aging.100298 pp 189—191
PDF How to Cite Special Collection on Longevity and Rapamycin

Review

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

Linda S. Steelman, William H. Chappell, Stephen L. Abrams, C. Ruth Kempf, Jacquelyn Long, Piotr Laidler, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Franca Stivala, Maria C. Mazzarino, Marco Donia, Paolo Fagone, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Michele Milella, Agostino Tafuri, Antonio Bonati, Jörg Bäsecke, Lucio Cocco, Camilla Evangelisti, Alberto M. Martelli, Giuseppe Montalto, Melchiorre Cervello, James A. McCubrey,
https://doi.org/10.18632/aging.100296 pp 192—222
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Research Papers

Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice

Amit Khanna, Senthilkumar Muthusamy, Ruqiang Liang, Harshini Sarojini, Eugenia Wang,
https://doi.org/10.18632/aging.100276 pp 223—236
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Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster

Nicholas Hoe, Chung M. Huang, Gary Landis, Marian Verhage, Daniel Ford, Junsheng Yang, Fred W. van Leeuwen, John Tower,
https://doi.org/10.18632/aging.100278 pp 237—261
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RasGrf1 deficiency delays aging in mice

Consuelo Borrás, Daniel Monleón, Raul López-Grueso, Juan Gambini, Leonardo Orlando, Federico V. Pallardó, Eugenio Santos, José Viña, Jaime Font de Mora,
https://doi.org/10.18632/aging.100279 pp 262—276
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The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice

Sophie Lachapelle, Steffi Oesterreich, Michel Lebel,
https://doi.org/10.18632/aging.100300 pp 277—290
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Lifespan extension and paraquat resistance in a ubiquinone-deficient Escherichia coli mutant depend on transcription factors ArcA and TdcA

Stavros Gonidakis, Steven E. Finkel, Valter D. Longo,
https://doi.org/10.18632/aging.100301 pp 291—303
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Research Perspectives

Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection

Ara B. Hwang, Seung-Jae Lee,
https://doi.org/10.18632/aging.100292 pp 304—310
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The Werner syndrome protein: linking the replication checkpoint response to genome stability

Pietro Pichierri, Francesca Ammazzalorso, Margherita Bignami, Annapaola Franchitto,
https://doi.org/10.18632/aging.100293 pp 311—318
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The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

Cheol Woong Ha, Won-Ki Huh,
https://doi.org/10.18632/aging.100299 pp 319—324
View Abstract PDF Full-Text How to Cite Special Collection on Longevity and Rapamycin

Does hypothalamic SIRT1 regulate aging?

Giorgio Ramadori, Roberto Coppari,
https://doi.org/10.18632/aging.100311 pp 325—328
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