Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 3, Issue 4

April 2011
pp 329—454

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Commentaries

A role for the cancer-associated miR-106b~25 cluster in neuronal stem cells

Barrie Peck, Almut Schulze,

https://doi.org/10.18632/aging.100302 pp 329—331

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Put on your thinking cap: G-quadruplexes, helicases, and telomeres

Robert M. Brosh Jr.,

https://doi.org/10.18632/aging.100307 pp 332—335

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A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis

João Pedro de Magalhães,

https://doi.org/10.18632/aging.100309 pp 336—337

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A new look at old compounds

Silvestre Alavez, Gordon J. Lithgow,

https://doi.org/10.18632/aging.100317 pp 338—339

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Conserved role of Ras-GEFs in promoting aging: from yeast to mice

Mario G. Mirisola, Valter D. Longo,

https://doi.org/10.18632/aging.100320 pp 340—343

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Ku circles the telomere?

Christian Sell,

https://doi.org/10.18632/aging.100321 pp 344—345

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Commentaries and Editorials

mTOR pathway activation in age-related retinal disease

Chen Zhao, Douglas Vollrath,

https://doi.org/10.18632/aging.100303 pp 346—347

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Gerosuppressant Metformin: less is more

Javier A. Menendez, Sílvia Cufí, Cristina Oliveras-Ferraros, Luciano Vellon, Jorge Joven, Alejandro Vazquez-Martin,

https://doi.org/10.18632/aging.100316 pp 348—362

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Review

Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in

Yme U. van der Velden, Anna-Pavlina G. Haramis,

https://doi.org/10.18632/aging.100319 pp 363—367

View Abstract PDF Full-Text How to Cite Special Collection on Tumor Suppressors

Research Papers

Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population

Daria Zhebrun, Yulia Kudryashova, Alina Babenko, Alexei Maslyansky, Natalya Kunitskaya, Daria Popcova, Alexandra Klushina, Elena Grineva, Anna Kostareva, Evgeny Shlyakhto,

https://doi.org/10.18632/aging.100305 pp 368—373

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Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans

Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana,

https://doi.org/10.18632/aging.100280 pp 374—379

View Abstract PDF Full-Text How to Cite Special Collection on Diet

Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C

Jenny CY Ho, Ting Zhou, Wing-Hon Lai, Yinghua Huang, Yau-Chi Chan, Xingyan Li, Navy LY Wong, Yanhua Li, Ka-Wing Au, Dongsheng Guo, Jianyong Xu, Chung-Wah Siu, Duanqing Pei, Hung-Fat Tse, Miguel Angel Esteban,

https://doi.org/10.18632/aging.100277 pp 380—390

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Pharmacological inhibition of NF-κB prolongs lifespan of Drosophila melanogaster

Alexey Moskalev, Mikhail Shaposhnikov,

https://doi.org/10.18632/aging.100314 pp 391—394

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Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells

Baomin Li, Sita Reddy, Lucio Comai,

https://doi.org/10.18632/aging.100308 pp 395—406

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Reversing the aging stromal phenotype prevents carcinoma initiation

Davina A. Lewis, Jeffrey B. Travers, Christiane Machado, Ally-Khan Somani, Dan F Spandau,

https://doi.org/10.18632/aging.100318 pp 407—416

View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Accelerated in vivo epidermal telomere loss in Werner syndrome

Naoshi Ishikawa, Ken-Ichi Nakamura, Naotaka Izumiyama-Shimomura, Junko Aida, Akio Ishii, Makoto Goto, Yuichi Ishikawa, Reimi Asaka, Masaaki Matsuura, Atsushi Hatamochi, Mie Kuroiwa, Kaiyo Takubo,

https://doi.org/10.18632/aging.100315 pp 417—429

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Research Perspectives

The physiological roles of Sirt1 in skeletal muscle

Patricia S. Pardo, Aladin M. Boriek,

https://doi.org/10.18632/aging.100312 pp 430—437

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Reversing B cell aging

Ramit Mehr, Doron Melamed,

https://doi.org/10.18632/aging.100313 pp 438—443

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Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis

Laurène Vetterli, Pierre Maechler,

https://doi.org/10.18632/aging.100304 pp 444—449

View Abstract PDF Full-Text How to Cite Special Collection on Diabetes

Hyperactive when young, hypoactive and overweight when aged: Connecting the dots in the story about locomotor activity, body mass, and aging in Trpv1 knockout mice

Samuel P. Wanner, Andras Garami, Andrej A. Romanovsky,

https://doi.org/10.18632/aging.100306 pp 450—454

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Featured Nobel Articles

Volume 3, Issue 4

Commentaries

Barrie Peck, Almut Schulze,

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Robert M. Brosh Jr.,

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João Pedro de Magalhães,

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Silvestre Alavez, Gordon J. Lithgow,

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Mario G. Mirisola, Valter D. Longo,

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Christian Sell,

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Commentaries and Editorials

Chen Zhao, Douglas Vollrath,

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Javier A. Menendez, Sílvia Cufí, Cristina Oliveras-Ferraros, Luciano Vellon, Jorge Joven, Alejandro Vazquez-Martin,

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Review

Yme U. van der Velden, Anna-Pavlina G. Haramis,

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Research Papers

Daria Zhebrun, Yulia Kudryashova, Alina Babenko, Alexei Maslyansky, Natalya Kunitskaya, Daria Popcova, Alexandra Klushina, Elena Grineva, Anna Kostareva, Evgeny Shlyakhto,

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Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana,

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Jenny CY Ho, Ting Zhou, Wing-Hon Lai, Yinghua Huang, Yau-Chi Chan, Xingyan Li, Navy LY Wong, Yanhua Li, Ka-Wing Au, Dongsheng Guo, Jianyong Xu, Chung-Wah Siu, Duanqing Pei, Hung-Fat Tse, Miguel Angel Esteban,

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Alexey Moskalev, Mikhail Shaposhnikov,

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Baomin Li, Sita Reddy, Lucio Comai,

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Davina A. Lewis, Jeffrey B. Travers, Christiane Machado, Ally-Khan Somani, Dan F Spandau,

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Naoshi Ishikawa, Ken-Ichi Nakamura, Naotaka Izumiyama-Shimomura, Junko Aida, Akio Ishii, Makoto Goto, Yuichi Ishikawa, Reimi Asaka, Masaaki Matsuura, Atsushi Hatamochi, Mie Kuroiwa, Kaiyo Takubo,

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Research Perspectives

Patricia S. Pardo, Aladin M. Boriek,

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Ramit Mehr, Doron Melamed,

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Laurène Vetterli, Pierre Maechler,