Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 11, Issue 20

31 October, 2019
pp 8730—9220

About the Cover

The cover features Figure 4 "SAMP8 mice display a spontaneous OA phenotype" from Malaise et al.

Explore This Issue

Editorials

Embrace the fat when getting old

Lorenz Adlung, Ido Amit, Eran Elinav,

https://doi.org/10.18632/aging.102341 pp 8730—8732

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Caveolin-1 regulates extracellular vesicle-miRNA packaging

Heedoo Lee, Jonathan M. Carnino, Yang Jin,

https://doi.org/10.18632/aging.102370 pp 8733—8735

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Self-renewal and differentiation in squamous cell carcinomas

Ana Sastre-Perona, Steven Hoang-Phou, Markus Schober,

https://doi.org/10.18632/aging.102381 pp 8736—8738

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Occult cardiac amyloidosis?

Oscar Westin, Finn Gustafsson, Emil Fosbøl,

https://doi.org/10.18632/aging.102383 pp 8739—8740

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Time-restricted eating and age-related muscle loss

Grant M. Tinsley, Antonio Paoli,

https://doi.org/10.18632/aging.102384 pp 8741—8742

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CD38-NAD⁺-Sirt1 axis in T cell immunotherapy

Shilpak Chatterjee, Paramita Chakraborty, Shikhar Mehrotra,

https://doi.org/10.18632/aging.102385 pp 8743—8744

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Research Papers

Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression

Xiaoxu Ge, Bojin Xu, Wenwei Xu, Lili Xia, Zhongqin Xu, Lisha Shen, Wenfang Peng, Shan Huang,

https://doi.org/10.18632/aging.102249 pp 8745—8759

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Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway

Feng Xu, Fu-Xing-Zi Li, Xiao Lin, Jia-Yu Zhong, Feng Wu, Su-Kang Shan, Chang-Ming Tan, Ling-Qing Yuan, Xiao-Bo Liao,

https://doi.org/10.18632/aging.102251 pp 8760—8776

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LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis

Xucheng Yang, Junxiao Yang, Pengfei Lei, Ting Wen,

https://doi.org/10.18632/aging.102264 pp 8777—8791

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Long non-coding RNA MALAT1 promotes cardiac remodeling in hypertensive rats by inhibiting the transcription of MyoD

Dan Li, Chunling Zhang, Jian Li, Jinna Che, Xuecheng Yang, Yuxin Xian, Xueli Li, Caixia Cao,

https://doi.org/10.18632/aging.102265 pp 8792—8809

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Increased calcium channel in the lamina propria of aging rat

Ji Min Kim, Hyoung-Sam Heo, Sung-Chan Shin, Hyun-Keun Kwon, Jin-Choon Lee, Eui-Suk Sung, Hyung-Sik Kim, Gi Cheol Park, Byung-Joo Lee,

https://doi.org/10.18632/aging.102284 pp 8810—8824

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ACADS acts as a potential methylation biomarker associated with the proliferation and metastasis of hepatocellular carcinomas

Diyu Chen, Xiaode Feng, Zhen Lv, Xiaofeng Xu, Yuejie Lu, Wenxuan Wu, Hao Wu, Hua Liu, Linping Cao, Sunyi Ye, Jianzhong Chen, Jian Wu,

https://doi.org/10.18632/aging.102292 pp 8825—8844

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COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway

Ruiqing Long, Zhuohui Liu, Jinghui Li, Hualin Yu,

https://doi.org/10.18632/aging.102300 pp 8845—8859

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Long non-coding SBF2-AS1 acting as a competing endogenous RNA to sponge microRNA-142-3p to participate in gemcitabine resistance in pancreatic cancer via upregulating TWF1

Yong-Qiang Hua, Yao-Dong Zhu, Guo-Qun Xie, Ke Zhang, Jie Sheng, Zhen-Feng Zhu, Zhou-Yu Ning, Hao Chen, Zhen Chen, Zhi-Qiang Meng, Lu-Ming Liu,

https://doi.org/10.18632/aging.102307 pp 8860—8878

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CD8+CXCR5+T cells infiltrating hepatocellular carcinomas are activated and predictive of a better prognosis

Linsen Ye, Yang Li, Hui Tang, Wei Liu, Yunhao Chen, Tianxing Dai, Rongpu Liang, Mengchen Shi, Shuhong Yi, Guihua Chen, Yang Yang,

https://doi.org/10.18632/aging.102308 pp 8879—8891

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TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway

Tian Yang, Tianhe Huang, Dongdong Zhang, Miao Wang, Balu Wu, Yufeng Shang, Safat Sattar, Lu Ding, Yin Liu, Hongqiang Jiang, Yuxing Liang, Fuling Zhou, Yongchang Wei,

https://doi.org/10.18632/aging.102329 pp 8892—8910

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Immature dendritic cells derived exosomes promotes immune tolerance by regulating T cell differentiation in renal transplantation

Xin-Lu Pang, Zhi-Gang Wang, Lei Liu, Yong-Hua Feng, Jun-Xiang Wang, Hong-Chang Xie, Xian-Lei Yang, Jin-Feng Li, Gui-Wen Feng,

https://doi.org/10.18632/aging.102346 pp 8911—8924

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Short-term efficacy of ticagrelor in acute ST-segment elevation myocardial infarction patients undergoing an emergency percutaneous coronary intervention

Bangming Cao, Fuzheng Qu, Xianliang Liu, Changzheng Gao, Qiang Fu, Chunying Jiang, Peng Wei, Qianqian Ma,

https://doi.org/10.18632/aging.102353 pp 8925—8936

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Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity

Yingqing Wang, Chun Chen, Wanling Huang, Maoxin Huang, Juhua Wang, Xiaochun Chen, Qinyong Ye,

https://doi.org/10.18632/aging.102357 pp 8937—8950

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LDLRAD2 overexpression predicts poor prognosis and promotes metastasis by activating Wnt/β-catenin/EMT signaling cascade in gastric cancer

Yucai Wei, Fan Zhang, Tong Zhang, Yating Zhang, Hao Chen, Furong Wang, Yumin Li,

https://doi.org/10.18632/aging.102359 pp 8951—8968

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Expression and significance of miR - 20b in retinal photoreceptor cells exposed to PCB₁₂₅₄

Xin Zhang, Qingyu Zhang, Yue Jiang, Shuchun Zhang, Qin Hong, Xirong Guo, Xia Chi, Meiling Tong,

https://doi.org/10.18632/aging.102360 pp 8969—8981

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Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart

Dan Liu, Linguo Wu, Ye Wu, Xin Wei, Wen Wang, Suli Zhang, Ming Yi, Jing Li, Huirong Liu, Xinliang Ma,

https://doi.org/10.18632/aging.102361 pp 8982—8997

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TIMP1 mRNA in tumor-educated platelets is diagnostic biomarker for colorectal cancer

Liu Yang, Qian Jiang, Dong-Zheng Li, Xin Zhou, Dong-Sheng Yu, Jian Zhong,

https://doi.org/10.18632/aging.102366 pp 8998—9012

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Melatonin induces progesterone production in human granulosa-lutein cells through upregulation of StAR expression

Lanlan Fang, Yiran Li, Sijia Wang, Yiping Yu, Yuxi Li, Yanjie Guo, Yang Yan, Ying-Pu Sun,

https://doi.org/10.18632/aging.102367 pp 9013—9024

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Differentially expressed autophagy-related genes are potential prognostic and diagnostic biomarkers in clear-cell renal cell carcinoma

Bangbei Wan, Bo Liu, Gang Yu, Yuan Huang, Cai Lv,

https://doi.org/10.18632/aging.102368 pp 9025—9042

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T5224, RSPO2 and AZD5363 are novel drugs against functional pituitary adenoma

Sheng Zhong, Bo Wu, Jiahui Li, Xinhui Wang, Shanshan Jiang, Fangfei Hu, Gaojing Dou, Yuan Zhang, Chunjia Sheng, Gang Zhao, Yunqian Li, Yong Chen,

https://doi.org/10.18632/aging.102372 pp 9043—9059

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Age-dependent relationship between preoperative serum aminotransferase and mortality after cardiovascular surgery

Jae-Sik Nam, Wook-Jong Kim, Sang-Mee An, Dae-Kee Choi, Ji-Hyun Chin, Eun-Ho Lee, In-Cheol Choi,

https://doi.org/10.18632/aging.102374 pp 9060—9074

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Sirtuin 3 attenuates neuroinflammation-induced apoptosis in BV-2 microglia

Dingzhou Zhou, Yugang Jiang,

https://doi.org/10.18632/aging.102375 pp 9075—9089

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Long noncoding RNA ARHGAP27P1 inhibits gastric cancer cell proliferation and cell cycle progression through epigenetically regulating p15 and p16

Guohua Zhang, Ying Xu, Chen Zou, Yinbing Tang, Jiawei Lu, Zhigang Gong, Gui Ma, Wenbo Zhang, Pengcheng Jiang,

https://doi.org/10.18632/aging.102377 pp 9090—9110

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Long noncoding RNA HULC promotes hepatocellular carcinoma progression

Hongwei Zhang, Zhibin Liao, Furong Liu, Chen Su, He Zhu, Yani Li, Ran Tao, Huifang Liang, Bixiang Zhang, Xuewu Zhang,

https://doi.org/10.18632/aging.102378 pp 9111—9127

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Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development

Olivier Malaise, Yassin Tachikart, Michael Constantinides, Marcus Mumme, Rosanna Ferreira-Lopez, Sandra Noack, Christian Krettek, Daniele Noël, Jing Wang, Christian Jorgensen, Jean-Marc Brondello,

https://doi.org/10.18632/aging.102379 pp 9128—9146

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Dysfunctional interactions between the default mode network and the dorsal attention network in subtypes of amnestic mild cognitive impairment

Junkai Wang, Jianghong Liu, Zhiqun Wang, Pei Sun, Kuncheng Li, Peipeng Liang,

https://doi.org/10.18632/aging.102380 pp 9147—9166

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Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells

Xunlin Li, Aimin Wu, Chen Han, Chen Chen, Tangjun Zhou, Kai Zhang, Xiao Yang, Zhiqian Chen, An Qin, Haijun Tian, Jie Zhao,

https://doi.org/10.18632/aging.102390 pp 9167—9187

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Narrative impairment, white matter damage and CSF biomarkers in the Alzheimer’s disease spectrum

Claudia Drummond, Gabriel Coutinho, Marina Carneiro Monteiro, Naima Assuncao, Alina Teldeschi, Andrea Silveira de Souza, Natalia Oliveira, Ivanei Bramati, Felipe Kenji Sudo, Bart Vanderboght, Carlos Otavio Brandao, Rochele Paz Fonseca, Ricardo de Oliveira-Souza, Jorge Moll, Paulo Mattos, Fernanda Tovar-Moll,

https://doi.org/10.18632/aging.102391 pp 9188—9208

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Overexpression of steroid sulfotransferase genes is associated with worsened prognosis and with immune exclusion in clear cell-renal cell carcinoma

Yuqing Li, Qiang Ding, Zuquan Xiong, Hui Wen, Chenchen Feng,

https://doi.org/10.18632/aging.102392 pp 9209—9219

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Correction

Correction for: LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

Marco Malavolta, Serena Dato, Francesco Villa, Francesco De Rango, Francesca Iannone, Anna Ferrario, Anna Maciag, Elena Ciaglia, Antonio D'amato, Albino Carrizzo, Andrea Basso, Fiorenza Orlando, Mauro Provinciali, Paolo Madeddu, Giuseppe Passarino, Carmine Vecchione, Giuseppina Rose, Annibale A. Puca,

https://doi.org/10.18632/aging.102398 pp 9220

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