The cover features Figure 7 "Scheme of epigenetic and molecular mechanisms changed in 5XFAD mice induced by pharmacological inhibition of G9a/GLP by UNC0642 “ from Griñán-Ferré et al.
Deschênes-Simard X, Rowell M, Ferbeyre G, . Metformin turns off the metabolic switch of pancreatic cancer. . 11:10793-10795. https://doi.org/10.18632/aging.102622
Chen H, Lin W, Lin P, Zheng M, Lai Y, Chen M, Zhang Y, Chen J, Lin X, Lin L, Lan Q, Yuan Q, Chen R, et al, . IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway. . 11:10796-10813. https://doi.org/10.18632/aging.102411
Zhao K, Zhang Y, Yuan H, Zhao M, Zhao D, . Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3. . 11:10814-10825. https://doi.org/10.18632/aging.102436
Su Y, Du Z, Zhong G, Ya Y, Bi J, Shi J, Chen L, Dong W, Lin T, . circ5912 suppresses cancer progression via inducing MET in bladder cancer. . 11:10826-10838. https://doi.org/10.18632/aging.102464
Chen J, Chen J, Huang J, Li Z, Gong Y, Zou B, Liu X, Ding L, Li P, Zhu Z, Zhang B, Guo H, Cai C, et al, . HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway. . 11:10839-10860. https://doi.org/10.18632/aging.102488
Jiang L, Zhao L, Bi J, Guan Q, Qi A, Wei Q, He M, Wei M, Zhao L, . Glycolysis gene expression profilings screen for prognostic risk signature of hepatocellular carcinoma. . 11:10861-10882. https://doi.org/10.18632/aging.102489
He Y, Zhou S, Deng F, Zhao S, Chen W, Wang D, Chen X, Hou J, Zhang J, Zhang W, Ding L, Tang J, Zhou Z, . Clinical and transcriptional signatures of human CD204 reveal an applicable marker for the protumor phenotype of tumor-associated macrophages in breast cancer. . 11:10883-10901. https://doi.org/10.18632/aging.102490
Zhang R, Liu Y, Liu H, Chen W, Fan H, Zhang J, Zhu J, . The long non-coding RNA SNHG12 promotes gastric cancer by activating the phosphatidylinositol 3-kinase/AKT pathway. . 11:10902-10922. https://doi.org/10.18632/aging.102493
Zheng X, Lv Y, Jin F, Wu X, Zhu J, Ruan Y, . Kainic acid hyperphosphorylates tau via inflammasome activation in MAPT transgenic mice. . 11:10923-10938. https://doi.org/10.18632/aging.102495
Ma L, Huang Y, Wang Z, Li J, Hou X, Shen X, Ou Y, Dong Q, Tan L, Yu J, Initiative ADN, . Metabolically healthy obesity reduces the risk of Alzheimer’s disease in elders: a longitudinal study. . 11:10939-10951. https://doi.org/10.18632/aging.102496
Sun H, Gong T, Jiang Y, Zhang S, Zhao Y, Wu Q, . Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: results from a global burden of disease study, 2017. . 11:10952-10991. https://doi.org/10.18632/aging.102497
Ren K, Li H, Zhou H, Liang Y, Tong M, Chen L, Zheng X, Zhao G, . Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1. . 11:10992-11009. https://doi.org/10.18632/aging.102498
Tan N, Liu J, Li P, Sun Z, Pan J, Zhao W, . Reactive oxygen species metabolism-based prediction model and drug for patients with recurrent glioblastoma. . 11:11010-11029. https://doi.org/10.18632/aging.102506
Sun K, Lin D, Feng Q, Li F, Qi Y, Huang C, Feng W, Yang C, Yan L, Ren M, . Parity is associated with albuminuria and chronic kidney disease: a population-based study. . 11:11030-11039. https://doi.org/10.18632/aging.102507
Wang C, Lin C, Huang Y, Wang S, Wang Y, Huang B, Lai Y, Weng S, Fong Y, Tang C, Lv Z, . Sphingosine-1-phosphate promotes PDGF-dependent endothelial progenitor cell angiogenesis in human chondrosarcoma cells. . 11:11040-11053. https://doi.org/10.18632/aging.102508
Liu Y, Zhou Y, Huang K, Li Y, Fang X, An L, Wang F, Chen Q, Zhang Y, Shi A, Yu S, Zhang J, . EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC. . 11:11054-11072. https://doi.org/10.18632/aging.102510
Ding J, Guan J, Rajah G, III DD, Li W, Wang Z, Ding Y, Ji X, Meng R, . Clinical and neuroimaging correlates among cohorts of cerebral arteriostenosis, venostenosis and arterio-venous stenosis. . 11:11073-11083. https://doi.org/10.18632/aging.102511
Li D, Liu Q, Lu X, Li Z, Wang C, Leung C, Wang Y, Peng C, Lin L, . α-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice. . 11:11084-11110. https://doi.org/10.18632/aging.102512
Zhou P, Yang C, Tang Z, Yi Y, Liu W, Tian M, Huang J, Gan W, Jiang X, Liu G, Wang H, Tao C, Fang Y, et al, . Daily decrease of post-operative alpha-fetoprotein by 9% discriminates prognosis of HCC: A multicenter retrospective study. . 11:11111-11123. https://doi.org/10.18632/aging.102513
Chen B, Lai J, Dai D, Chen R, Li X, Liao N, . JAK1 as a prognostic marker and its correlation with immune infiltrates in breast cancer. . 11:11124-11135. https://doi.org/10.18632/aging.102514
Yin J, Nielsen M, Carcione T, Li S, Shi J, . Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway. . 11:11148-11156. https://doi.org/10.18632/aging.102516
Lin Y, Liang R, Ye J, Li Q, Liu Z, Gao X, Piao X, Mai R, Zou D, Ge L, . A twenty gene-based gene set variation score reflects the pathological progression from cirrhosis to hepatocellular carcinoma. . 11:11157-11169. https://doi.org/10.18632/aging.102518
Yu W, An S, Shao T, Xu H, Chen H, Ning J, Zhou Y, Chai X, . Active compounds of herbs ameliorate impaired cognition in APP/PS1 mouse model of Alzheimer’s disease. . 11:11186-11201. https://doi.org/10.18632/aging.102522
Su Y, Feng W, Zhong G, Ya Y, Du Z, Shi J, Chen L, Dong W, Lin T, . ciRs-6 upregulates March1 to suppress bladder cancer growth by sponging miR-653. . 11:11202-11223. https://doi.org/10.18632/aging.102525
Yang C, Tan Y, Li S, Zhou J, Wang Q, Wang Y, Xie Y, Chen L, Li J, Fang C, Kang C, . Genomic landscapes by multiregion sequencing combined with circulation tumor DNA detection contribute to molecular diagnosis in glioblastomas. . 11:11224-11243. https://doi.org/10.18632/aging.102526
Hall BS, Barnett YA, Crofts JJ, Chuzhanova N, . Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. . 11:11244-11267. https://doi.org/10.18632/aging.102527
van Gastel J, Leysen H, Santos-Otte P, Hendrickx JO, Azmi A, Martin B, Maudsley S, . The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. . 11:11268-11313. https://doi.org/10.18632/aging.102528
He Q, Huang L, Yan D, Bi J, Yang M, Huang J, Lin T, . CircPTPRA acts as a tumor suppressor in bladder cancer by sponging miR-636 and upregulating KLF9. . 11:11314-11328. https://doi.org/10.18632/aging.102530
Wang H, Liu K, Chi Z, Zhou X, Ren G, Zhou R, Li Y, Tang X, Wang XJ, . Interplay of MKP-1 and Nrf2 drives tumor growth and drug resistance in non-small cell lung cancer. . 11:11329-11346. https://doi.org/10.18632/aging.102531
Lin T, Sung Y, Ko T, Lee C, Lin L, Juang JJ, Wu C, . Risk of ischemic stroke in patients with hypertrophic cardiomyopathy in the absence of atrial fibrillation – a nationwide cohort study. . 11:11347-11357. https://doi.org/10.18632/aging.102532
Ma J, Fang L, Yang Q, Hibberd S, Du WW, Wu N, Yang BB, . Posttranscriptional regulation of AKT by circular RNA angiomotin- like 1 mediates chemoresistance against paclitaxel in breast cancer cells. . 11:11369-11381. https://doi.org/10.18632/aging.102535
Liu W, Xiong X, Mo Y, Chen W, Li M, Liang R, Zhang Z, Zhang Z, . Young age at diagnosis is associated with better prognosis in stage IV breast cancer. . 11:11382-11390. https://doi.org/10.18632/aging.102536
Qin W, Li J, Zhu R, Gao S, Fan J, Xia M, Zhao RC, Zhang J, . Melatonin protects blood-brain barrier integrity and permeability by inhibiting matrix metalloproteinase-9 via the NOTCH3/NF-κB pathway. . 11:11391-11415. https://doi.org/10.18632/aging.102537
Liu Y, Wu L, Ao H, Zhao M, Leng X, Liu M, Ma J, Zhu J, . Prognostic implications of autophagy-associated gene signatures in non-small cell lung cancer. . 11:11440-11462. https://doi.org/10.18632/aging.102544
Sun J, Zheng J, Li Y, Yan M, Li P, Ma L, . LncRNA EPIC1 downregulation mediates hydrogen peroxide-induced neuronal cell injury. . 11:11463-11473. https://doi.org/10.18632/aging.102545
Wan B, Liu B, Huang Y, Yu G, Lv C, . Prognostic value of immune-related genes in clear cell renal cell carcinoma. . 11:11474-11489. https://doi.org/10.18632/aging.102548
Shao N, Su H, Ye D, . Conditional disease-free survival in high-risk renal cell carcinoma treated with sunitinib. . 11:11490-11503. https://doi.org/10.18632/aging.102549
Peng Q, Chen B, Wang H, Zhu Y, Wu J, Luo Y, Zuo G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He T, et al, . Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. . 11:11520-11540. https://doi.org/10.18632/aging.102552
Jeong Han Lee, Mincheol Kang, Seojin Park, Maria C. Perez-Flores, Xiao-Dong Zhang, Wenying Wang, Michael Anne Gratton, Nipavan Chiamvimonvat, Ebenezer N. Yamoah,
Lee JH, Kang M, Park S, Perez-Flores MC, Zhang X, Wang W, Gratton MA, Chiamvimonvat N, Yamoah EN, . The local translation of KNa in dendritic projections of auditory neurons and the roles of KNa in the transition from hidden to overt hearing loss. . 11:11541-11564. https://doi.org/10.18632/aging.102553
Xia Y, Lu Z, Wang S, Hu L, . Nrf2 activation mediates tumor-specific hepatic stellate cells-induced DIgR2 expression in dendritic cells. . 11:11565-11575. https://doi.org/10.18632/aging.102554
Nie R, Yuan S, Wang Y, Chen Y, Cai Y, Chen S, Li S, Zhou J, Chen G, Luo T, Zhou Z, Li Y, . Robust immunoscore model to predict the response to anti-PD1 therapy in melanoma. . 11:11576-11590. https://doi.org/10.18632/aging.102556
Li S, Zheng K, Pei Y, Wang W, Zhang X, . Long noncoding RNA NR2F1-AS1 enhances the malignant properties of osteosarcoma by increasing forkhead box A1 expression via sponging of microRNA-483-3p. . 11:11609-11623. https://doi.org/10.18632/aging.102563
Chang M, Pan Y, Wu H, Lu Y, Liao W, Yeh C, Lee J, Jeng J, . Stimulation of MMP-9 of oral epithelial cells by areca nut extract is related to TGF-β/Smad2-dependent and –independent pathways and prevented by betel leaf extract, hydroxychavicol and melatonin. . 11:11624-11639. https://doi.org/10.18632/aging.102565
Li D, Zhang L, Liu Y, Sun H, Onwuka JU, Zhao Z, Tian W, Xu J, Zhao Y, Xu H, . Specific DNA methylation markers in the diagnosis and prognosis of esophageal cancer. . 11:11640-11658. https://doi.org/10.18632/aging.102569
Guo H, Liu H, Jian Z, Cui H, Fang J, Zuo Z, Deng J, Li Y, Wang X, Zhao L, Geng Y, Ouyang P, Lai W, et al, . Nickel induces inflammatory activation via NF-κB, MAPKs, IRF3 and NLRP3 inflammasome signaling pathways in macrophages. . 11:11659-11672. https://doi.org/10.18632/aging.102570
Zou D, Li R, Huang X, Chen G, Liu Y, Meng Y, Wang Y, Wu Y, Mao Y, . Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease. . 11:11673-11685. https://doi.org/10.18632/aging.102571
Cristina Ramos-Pérez, Margaret Dominska, Laura Anaissi-Afonso, Sara Cazorla-Rivero, Oliver Quevedo, Isabel Lorenzo-Castrillejo, Thomas D. Petes, Félix Machín,
Ramos-Pérez C, Dominska M, Anaissi-Afonso L, Cazorla-Rivero S, Quevedo O, Lorenzo-Castrillejo I, Petes TD, Machín F, . Cytological and genetic consequences for the progeny of a mitotic catastrophe provoked by Topoisomerase II deficiency. . 11:11686-11721. https://doi.org/10.18632/aging.102573
Angela Mena Perri, Valter Agosti, Erika Olivo, Antonio Concolino, MariaTeresa De Angelis, Laura Tammè, Claudia Vincenza Fiumara, Giovanni Cuda, Domenica Scumaci,
Ni H, Zhao Y, Ji Y, Shen J, Xiang M, Xie Y, . Adipose-derived stem cells contribute to cardiovascular remodeling. . 11:11756-11769. https://doi.org/10.18632/aging.102491
Triaca V, Carito V, Fico E, Rosso P, Fiore M, Ralli M, Lambiase A, Greco A, Tirassa P, . Cancer stem cells-driven tumor growth and immune escape: the Janus face of neurotrophins. . 11:11770-11792. https://doi.org/10.18632/aging.102499
Guachalla LM, Ju Z, Koziel R, von Figura G, Song Z, Fusser M, Epe B, Jansen-Dürr P, Rudolph KL, . Correction for: Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. . 11:11793-11794. https://doi.org/10.18632/aging.102602